InstaDeepAI/instanovo-phospho-v1.0.0

# InstaNovo: De novo Peptide Sequencing Model ## Model Description

# InstaNovo: De novo Peptide Sequencing Model ## Model Description

InstaNovoPlus is a diffusion-based model for de novo peptide sequencing from mass spectrometry data. This model leverages multinomial diffusion for accurate, database-free peptide identification for large-scale proteomics experiments.

Winnow recalibrates confidence scores and provides FDR control for de novo peptide sequencing (DNS) workflows. This repository hosts a pretrained, general-purpose calibrator that maps raw InstaNovo model confidences and complementary features (mass error, retention time, beam features, fragment…

Winnow recalibrates confidence scores and provides FDR control for de novo peptide sequencing (DNS) workflows. This repository hosts a calibrator trained on the HeLa Single Shot dataset as referenced in our paper: De novo peptide sequencing rescoring and FDR estimation with Winnow.

iona-denoise-400m scores every peak of a tandem mass spectrum (MS/MS) as signal or noise. It is the Iona 400m encoder with a per-peak classification head, fine-tuned for noise-peak detection.