Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

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A compact protein language model distilled from ProtGPT2 using complementary-regularizer distillation---a method that combines uncertainty-aware position weighting with calibration-aware label smoothing to achieve 54% better perplexity than standard knowledge distillation at 9.4x compression.

Active55 months ago
Python

A compact protein language model distilled from ProtGPT2 using complementary-regularizer distillation---a method that combines uncertainty-aware position weighting with calibration-aware label smoothing to achieve 87% better perplexity than standard knowledge distillation at 20x compression.

Active145 months ago
Python
Active7.1K6 months ago
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Active3146 months ago
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Active10.8K6 months ago
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# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-BACE-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Active2936 months ago

# ibm-research/biomed.sm.mv-te-84m biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of molecules in a foundation model…

Active2K6 months ago

## Model Description This repository contains the weights for the Borzoi model, a model designed to predict functional genomic tracks from genomic DNA sequences.

Idle06 months ago
Idle6.5K6 months ago
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Idle18K6 months ago
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The complete neuron-to-neuron connectivity matrix extracted from a nanometer-resolution reconstruction of human temporal cortex (H01 dataset, Google/Harvard/Lichtman Lab).

Idle166 months ago

ONNX export of the Cellpose cpsam (Cellpose-SAM) model for cell segmentation in microscopy images.

Idle06 months ago

Model weights, configurations, and vocabularies for CpGPT: A Foundation Model for DNA Methylation.

Idle06 months ago

![Figure #](

Idle5.9K6 months ago

🌟 Github | 📥 Model Download | 📚 Dataset | 📄 Paper Link | 🌐 Project Page

Idle426 months ago
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Idle06 months ago

From Inquiry to Decision: Building Trustworthy Medical AI

Idle206 months ago
Python

A Neural Machine Translation (NMT) model based on a custom Transformer (Encoder-Decoder) architecture, trained from scratch. This model is designed to translate English sentences into Hebrew using multilingual encoding and specialized layer configurations.

Idle116 months ago
Python

Gengram is a novel conditional memory module designed for genomic foundation models (GFMs) that introduces explicit motif memory retrieval to enhance Transformer-based DNA sequence modeling. Unlike traditional GFMs that rely on dense computation to implicitly infer multi-nucleotide motifs, Gengram…

Idle06 months ago
Idle06 months ago
Idle06 months ago

WiNGPT 是一个基于GPT的医疗垂直领域大模型,旨在将专业的医学知识、医疗信息、数据融会贯通,为医疗行业提供智能化的医疗问答、诊断支持和医学知识等信息服务,提高诊疗效率和医疗服务质量。

Idle8.1K6 months ago
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Matěj Pekár, Vít Musil, Rudolf Nenutil, Petr Holub, Tomáš Brázdil

Idle3167 months ago
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This model is a fine-tuned version of google/medgemma-1.5-4b-it specialized for mammogram analysis and breast imaging interpretation.

Idle07 months ago

AVAILABLE NOW THE LATEST ITERATION OF THE ALOE FAMILY! ALOE BETA 8B AND ALOE BETA 70B VERSIONS. These include: Better overall performance More thorough alignment and safety * License compatible with more uses

Idle4997 months ago
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Aloe: A Family of Fine-tuned Open Healthcare LLMs

Idle1.3K7 months ago
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While large language models (LLMs) have achieved impressive progress, their application in scientific domains such as chemistry remains hindered by shallow domain understanding and limited reasoning capabilities. In this work, we focus on the specific field of chemistry and develop a Chemical…

Idle737 months ago

ChemDFM-v2.0 is the latest non-thinking model of ChemDFM, the pioneering open-sourced dialogue foundation model for Chemistry and molecule science.

Idle1.3K7 months ago

Unsloth Dynamic 2.0 achieves superior accuracy & outperforms other leading quants.

Idle9.2K7 months ago
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PII Detection Model | 44M Parameters | Open Source

Idle27K7 months ago
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PII Detection Model | 434M Parameters | Open Source

Idle105.4K7 months ago
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An efficient machine-learning interatomic potential for molecular dynamics simulations of organic and biological systems trained on an extension of the SPICE2 dataset. The model comes in two sizes (S and M).

Idle07 months ago

This is a MobileViT (Small) model fine-tuned on the Processed Diabetic Retinopathy dataset.

Idle47 months ago
Python

> [!NOTE] > Inspired by the thought of: what if you could speak to an offline medical assistant that doesn't decline to answer some of your questions?

Idle267 months ago
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TM-Vec 2: Transformer-based architecture for remote homology detection.

Idle1.2K8 months ago

The MediPhi Model Collection comprises 7 small language models of 3.8B parameters from the base model Phi-3.5-mini-instruct specialized in the medical and clinical domains. The collection is designed in a modular fashion. Five MediPhi experts are fine-tuned on various medical corpora (i.e.

Idle3258 months ago
Python

The MediPhi Model Collection comprises 7 small language models of 3.8B parameters from the base model Phi-3.5-mini-instruct specialized in the medical and clinical domains. The collection is designed in a modular fashion. Five MediPhi experts are fine-tuned on various medical corpora (i.e.

Idle7948 months ago
Python

The MediPhi Model Collection comprises 7 small language models of 3.8B parameters from the base model Phi-3.5-mini-instruct specialized in the medical and clinical domains. The collection is designed in a modular fashion. Five MediPhi experts are fine-tuned on various medical corpora (i.e.

Idle1328 months ago
Python

The MediPhi Model Collection comprises 7 small language models of 3.8B parameters from the base model Phi-3.5-mini-instruct specialized in the medical and clinical domains. The collection is designed in a modular fashion. Five MediPhi experts are fine-tuned on various medical corpora (i.e.

Idle1K8 months ago
Python

The MediPhi Model Collection comprises 7 small language models of 3.8B parameters from the base model Phi-3.5-mini-instruct specialized in the medical and clinical domains. The collection is designed in a modular fashion. Five MediPhi experts are fine-tuned on various medical corpora (i.e.

Idle2K8 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Idle1818 months ago
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## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology. This model version was continually pretrained on ~14 million cancer transcriptomes…

Idle168 months ago
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## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Idle318 months ago
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## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Idle178 months ago
Python

## Model Overview PlantBiMoE is a DNA language model trained on 42 representative plant species genomes. More specifically, PlantBiMoE uses the BiMamba and SparseMoE architecture with a masked language modeling objective to leverage highly available genotype data from 42 different plant speices to…

Idle108 months ago

For a convenient overview and download list, visit our model page for this model.

Idle1668 months ago
Python

Support our open-source dataset and model releases!

Idle608 months ago
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