Find open-source science resources
A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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229 of 7,055 resources
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HarshBhanushali7705/medgemma-27b-text-it-GPTQ-4bit
by HarshBhanushali7705This repository contains a 4-bit GPTQ quantized version of google/medgemma-27b-text-it, optimized for high-throughput inference using vLLM and the Marlin kernel.
alimotahharynia/DrugGen-2
by alimotahharynia# DrugGen 2: A disease-aware language model for enhancing drug discovery DrugGen-2 is a disease‑aware language model specialized for generating drug-like SMILES structures based on both disease pathways and protein sequence.
CladeTeam/CENO-P-1B
by CladeTeamCENO-P-1B is the multi-species alignment (MSA) post-trained variant of the 1B CENO DNA foundation model, for variant effect prediction (VEP). It carries intraencodingpattern in its config and ships the MSA scoring path (modelingcenop.py), which consumes a per-token seq_idx to score packed MSA…
CladeTeam/CENO-1B-131k
by CladeTeamCENO-1B-131k is the long-context (131k) checkpoint of the 1B CENO DNA foundation model — a causal language model over genomic sequence built on a Nemotron-H Mamba / Attention / Mixture-of-Experts hybrid backbone (no MSA inputs).
CladeTeam/CENO-80M-1m
by CladeTeamCENO-80M-1m is the long-context (1M) checkpoint of the 80M CENO DNA foundation model — a causal language model over genomic sequence built on a Nemotron-H Mamba / Attention / Mixture-of-Experts hybrid backbone (no MSA inputs).
reaperdoesntknow/Qwen3-1.7B-Distilled-30B-A3B
by reaperdoesntknowA 1.7B-parameter causal language model distilled from Qwen3-30B-A3B on 6,122 STEM chain-of-thought samples using discrepancy-informed knowledge distillation. The training objective emphasizes proof structure, detects reasoning pivot tokens through token-level divergence dynamics, smooths…
King3Djbl/nexus-medical-GGUF
by King3Djbl> NEXUS domain specialist for medical Q&A and clinical reasoning — lightweight & uncensored.
fableforge-ai/NEXUS-Medical
by fableforge-ai> NEXUS domain specialist for medical Q&A and clinical reasoning — lightweight & uncensored.
!Screenshot 2026-07-05 at 2.33.47 AM
DaisyChainAI/daisychain-genomics
by DaisyChainAIPippinlitli/evolva-qwen-0.5b-heretic
by PippinlitliHeretic-abliterated version of Qwen/Qwen2.5-0.5B-Instruct for the Evolva drug discovery pipeline.
zsyjsld/Xinghe1-9B
by zsyjsldXinghe1-9B (杏核) is a specialized large language model fine-tuned for the formalization, computational derivation, and clinical reasoning of Huangdi Neijing. It is based on the Qwen3.5-9B-Instruct architecture and trained using the V3 Double-Purity SFT dataset.
SeongryongJung/Qwen3-4B-Chemistry-SDPO
by SeongryongJungThis repository contains Chemistry fine-tuned Qwen3-4B checkpoints from the local SciKnowEval-style generalization setup.
👋 Join our LiGHT community. 📖 Check out the MeditronFO blog and MeditronFO preprint. 🔜 If you are a clinician join the MOOVE initiative here.
FrenchCastle/sexology-v4
by FrenchCastleSexo-FR is a French-language conversational language model that provides reliable, caring, and evidence-based sexual health information (information en santé sexuelle). It is part of a French public-health initiative whose goal is to make trustworthy sexual-health information more accessible to the…
👋 Join our LiGHT community. 📖 Check out the MeditronFO blog and MeditronFO preprint. 🔜 If you are a clinician join the MOOVE initiative here.
trillionlabs/Gravity-bio-16B-A3B
by trillionlabsGravity-bio-16B-A3B is a biology-focus midtrained model derived from Gravity-16B-A3B-Base. It uses the same sparse Mixture-of-Experts (MoE) architecture and tokenizer as Gravity-16B-A3B-Base, with additional midtraining for biological understanding on TheBioCollection corpus.
EPFLiGHT/Meditron3-8B
by EPFLiGHTfairydance/molexar-10m-base
by fairydanceMolexar-10M Base is the unconditional base model for Molexar, a unified multimodal molecular foundation model for drug design. It is trained as an autoregressive molecular language model over Fragment-SELFIES, a BRICS-fragment molecular language with validity-preserving decoding and…
fairydance/molexar-10m-omni
by fairydanceMolexar-10M Omni is the universal multi-condition model for Molexar, a unified multimodal molecular foundation model for drug design. It starts from fairydance/molexar-10m-base and is supervised fine-tuned to generate Fragment-SELFIES molecules under scalar molecular-property,…
iti-visual-analytics/GRamma-12B
by iti-visual-analyticsGRamma-12B is a 12-billion-parameter instruction-tuned language model specialized for the Greek medical domain. It is built on top of Gemma 3 12B Instruct and adapted through parameter-efficient fine-tuning on a collection of Greek and bilingual medical question-answering data.
QLoRA adapter for Llama-3.1-8B-Instruct, fine-tuned on PubMedQA for yes / no / maybe biomedical question answering (run5).
BioMatrix is a multimodal biological foundation model that natively integrates 1D sequences, 3D structures, and natural language for both molecules and proteins within a single decoder-only architecture.
nikitaredy/medictron-7B
by nikitaredyA domain-adapted clinical LLM fine-tuned on synthetic Indian medical Q&A records using QLoRA (4-bit quantization) with Unsloth 2x speedup. Built to power the conversational AI layer.
ProtGPT3-MSA is a multiple-sequence, homolog-conditioned autoregressive protein language model. It is part of the ProtGPT3 family, an open-source suite of promptable and aligned protein language models for protein sequence generation.
weblab-LLM-M/AscleLM-1-10B
by weblab-LLM-MBabajaan/KAU-BioMedLLM
by BabajaanKAU-BioMedLLM is a research prototype for source-grounded biomedical variant interpretation. The current public release contains the LoRA adapter and documentation for a guarded report-generation system built around a curated biomedical evidence panel, citation enforcement, and abstention when…
## Important Notice If you are using GENERator for sequence generation, please ensure that the length of each input sequence is a multiple of 6. This can be achieved by either: 1. Padding the sequence on the left with 'A' (left padding); 2. Truncating the sequence from the left (left truncation).
tokyotech-llm/Medical-GPT-OSS-Swallow-120B
by tokyotech-llmMedical-GPT-OSS-Swallow-120B is a medical-domain language model based on tokyotech-llm/GPT-OSS-Swallow-120B-RL-v0.1. It is designed to support research and development toward safe and trustworthy AI for Japanese clinical settings.
tokyotech-llm/Medical-Qwen3-Swallow-30B-A3B
by tokyotech-llmMedical-Qwen3-Swallow-30B-A3B is a medical-domain language model based on tokyotech-llm/Qwen3-Swallow-30B-A3B-RL-v0.2. It is designed to support research and development toward safe and trustworthy AI for Japanese clinical settings.
qwen35-9b-medical is an Ollama/GGUF medical assistant profile based on Jackrong/Qwen3.5-9B-Claude-4.6-Opus-Reasoning-Distilled-v2-GGUF, distributed locally through the Ollama model kwangsuklee/Qwen3.5-9B.Q4KM-Claude-4.6-Opus-Reasoning-Distilled-v2.
mradermacher/gemma4-12b-bioinfo-GGUF
by mradermacherFor a convenient overview and download list, visit our model page for this model.
# Instruction For more information, visit our GitHub repository: https://github.com/medfound/medfound
This repository contains GGUF files for gemma4-12b-bioinfo, a fine-tuned Gemma 4 12B model for bioinformatics and computational biology.
gemma4-12b-bioinfo is a fine-tuned Gemma 4 12B instruction model for bioinformatics, genomics, and computational biology question answering.
modelid = "DuanYi/R3LMHepG2"
*GenerRNA is a generative pre-trained language model for de novo RNA sequence design. It is a Transformer (decoder-only, GPT-style) model that learns the "language" of RNA from millions of natural sequences and can generate novel, realistic RNA sequences without any structural input, functional…
Wildstash/DentalGPT
by WildstashPhysicsWallahAI/Aryabhata-2.0
by PhysicsWallahAIAryabhata 2 is a reasoning-focused language model developed by PhysicsWallah for competitive STEM examinations (JEE, NEET). It is obtained by post-training GPT-OSS-20B via reinforcement learning on a curated curriculum of Physics, Chemistry, Mathematics, and General Reasoning questions — achieving…
FINAL-Bench/Darwin-218B-Delphi
by FINAL-Bench> VIDRAFT FINAL-Bench — chemistry-specialized 218B MoE, served via the DELPHI 5-Phase inference cascade.
HealthJudge is a domain-adapted helpfulness evaluator for health-related Community Notes. It is designed to judge whether a note provides helpful context for a potentially misleading social-media post, following the Community Notes helpfulness criteria.
## Model Description ProtGPT3-112M is a single-sequence autoregressive protein language model for protein sequence generation. It is the smallest model in the ProtGPT3 family, an open-source suite of promptable and aligned protein language models ranging from 112M to 10B parameters.
ProtGPT3-10B is a single-sequence autoregressive protein language model for protein sequence generation. It is the largest model in the ProtGPT3 family, an open-source suite of promptable and aligned protein language models ranging from 112M to 10B parameters.
poolside-laguna-hackathon/protein-ligand-design
by poolside-laguna-hackathon!Protein-ligand interaction header
pankajpandey-dev/Carbon-3B-GGUF
by pankajpandey-devGGUF quantizations of HuggingFaceBio/Carbon-3B — a generative DNA foundation model — for efficient inference with llama.cpp.
UCL-CSSB/PlasmidGPT
by UCL-CSSBA HuggingFace-compatible repackaging of PlasmidGPT (Shao, 2024) — a GPT-2-style decoder pretrained on 153k engineered plasmid sequences from Addgene. Loadable with standard AutoModelForCausalLM and AutoTokenizer. Used as the base for PlasmidGPT-SFT and PlasmidGPT-GRPO.
Hamdan003/inventmol-r1
by Hamdan003Target-Conditioned Molecular Ideation Model for Drug Discovery Research