vandijklab/C2S-Scale-Gemma-2-27B

Genos-m is a foundation model for human-associated microbial genomes. It is trained to model microbial DNA sequences at single-nucleotide resolution and supports ultra-long genomic contexts up to one million tokens.

gemma4-12b-bioinfo is a fine-tuned Gemma 4 12B instruction model for bioinformatics, genomics, and computational biology question answering.

## Important Notice If you are using GENERator for sequence generation, please ensure that the length of each input sequence is a multiple of 6. This can be achieved by either: 1. Padding the sequence on the left with 'A' (left padding); 2. Truncating the sequence from the left (left truncation).

This repository contains GGUF files for gemma4-12b-bioinfo, a fine-tuned Gemma 4 12B model for bioinformatics and computational biology.

A compact protein language model distilled from ProtGPT2 using complementary-regularizer distillation---a method that combines uncertainty-aware position weighting with calibration-aware label smoothing to achieve 31% better perplexity than standard knowledge distillation at 3.8x compression.