SCYN

Single cell CNV profiling method using dynamic programming. To install R package SCOPE, please refer to the README of SCOPE. SCYN integrates the SCOPE to get the cell-by-bin reads depth matrix and perform the normalization. SCYN mainly focuses on finding the optimal CNV segmentation profiling using dynamic programming. Platform for Single Cell DNA Visualization. The recent advance of single-cell copy number variation analysis plays an essential role in addressing intratumor heterogeneity, identifying tumor subgroups, and restoring tumor evolving trajectories at single-cell resolution.