Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

2,419 of 6,573 resources

Showing 150

Active46 days ago
Makefile
CC-BY-4.0

With the DataPLANT biology ontology (DPBO), DataPLANT provides an intermediate ontology that acts as a broker and bridge between the individual researcher/domain experts and main ontology providers. DPBO enables easy and agile collection of missing vocabulary as well as relationships between terms for (meta)data annotation using DataPLANT’s Swate tool.

Active76 days ago
F#
CC-BY-4.0

Identifiers in the GTN correspond to training materials in various formats (markdown, slides, video). The users can apply learned concepts directly within the framework via galaxy workflows.

Active3671 week ago
HTML
MIT
Active641 week ago
Python

The Common Core Ontologies (CCO) comprise twelve ontologies that are designed to represent and integrate taxonomies of generic classes and relations across all domains of interest. CCO is a mid-level extension of Basic Formal Ontology (BFO), an upper-level ontology framework widely used to structure and integrate ontologies in the biomedical domain (Arp, et al., 2015). BFO aims to represent the most generic categories of entity and the most generic types of relations that hold between them, by defining a small number of classes and relations. CCO then extends from BFO in the sense that every class in CCO is asserted to be a subclass of some class in BFO, and that CCO adopts the generic relations defined in BFO (e.g., has_part) (Smith and Grenon, 2004). Accordingly, CCO classes and relations are heavily constrained by the BFO framework, from which it inherits much of its basic semantic relationships.

Active3631 week ago
Python
BSD-3-Clause

The Bioregistry is integrative meta-registry of biological databases, ontologies, and nomenclatures that is backed by an open database.

Active1461 week ago
HTML
CC0-1.0

An issue on the Gene Ontology GitHub issue tracker

Active2511 week ago
Makefile
CC-BY-4.0

Bioschemas aims to improve the Findability on the Web of life sciences resources such as datasets, software, and training materials. It does this by encouraging people in the life sciences to use Schema.org markup in their websites so that they are indexable by search engines and other services. Bioschemas encourages the consistent use of markup to ease the consumption of the contained markup across many sites. This structured information then makes it easier to discover, collate, and analyse distributed resources. [from BioSchemas.org]

Active651 week ago
HTML
CC-BY-SA-4.0

An EMMO-based domain ontology for atomistic and electronic modelling.

Active11 week ago
Python
CC-BY-4.0

The Basic Register of Thesauri, Ontologies & Classifications (BARTOC) is a database of Knowledge Organization Systems and KOS related registries. The main goal of BARTOC is to list as many Knowledge Organization Systems as possible at one place in order to achieve greater visibility, highlight their features, make them searchable and comparable, and foster knowledge sharing. BARTOC includes any kind of KOS from any subject area, in any language, any publication format, and any form of accessibility. BARTOC’s search interface is available in 20 European languages and provides two search options: Basic Search by keywords, and Advanced Search by taxonomy terms. A circle of editors has gathered around BARTOC from all across Europe and BARTOC has been approved by the International Society for Knowledge Organization (ISKO).

Active291 week ago
JavaScript
MIT

Vitro is a full stack framework for building semantic web applications. It is not domain specific.

Active1171 week ago
Java
BSD-3-Clause
Active31 week ago
CC-BY-4.0

The primary goal of this ontology is to standardize the representation of molecular simulation data, processes, and methodologies across disparate simulation platforms, engines (e.g., GROMACS, AMBER, NAMD), and analysis tools, while ensuring these terms are interoperable with existing life sciences ontologies

Active71 week ago
Python
Active3941 week ago
Python
BSD-3-Clause

The System Package Data Exchange™ (SPDX®) specification is an open standard designed to represent systems containing software components as Software Bill of Materials (SBOMs). Additionally, SPDX supports AI, data, and security references, making it suitable for a wide range of risk management use cases. This _spdx3_ prefix is for SPDX 3.x versions. For earlier versions, use _spdx.term_.

Active3781 week ago
Python
Community-Spec-1.0

A large RDF store built from American governmental data. This semantic space has a mixture of direct terms and subspaces.

Active312 weeks ago
TypeScript
Apache-2.0

The information resource registry is a listing of data sources present in the NCATS Data Translator system. Each information resource has an identifier, a short description, and a URL to more information about that resource.

Active62 weeks ago
Python
Apache-2.0

BioTools is a registry of databases and software with tools, services, and workflows for biological and biomedical research.

Active892 weeks ago
HTML
GPL-3.0

SO is a collaborative ontology project for the definition of sequence features used in biological sequence annotation. It is part of the Open Biomedical Ontologies library.

Active1052 weeks ago
Makefile
CC-BY-4.0

EMMO is a multidisciplinary effort to develop a standard representational framework (the ontology) for applied sciences. It is based on physics, analytical philosophy and information and communication technologies. It has been instigated by materials science to provide a framework for knowledge capture that is consistent with scientific principles and methodologies. (from GitHub)

Active902 weeks ago
Python
CC-BY-4.0

OEO is a domain reference ontology for energy system modeling.

Active1572 weeks ago
Python
CC0-1.0

An _gentle_ implementation of the Unified Foundational Ontology (UFO), which is an upper level ontology like BFO that is concerned with e.g. expressing temporal relationships between events.

Active452 weeks ago
CC-BY-4.0

A RDF vocabulary for OER content on the web.

Active222 weeks ago
TypeScript
MIT

Voc4Cat is a [SKOS](https://www.w3.org/TR/2009/REC-skos-reference-20090818/) vocabulary for the catalysis disciplines. The vocabulary was created in the [NFDI4Cat](http://www.nfdi4cat.org/) initiative. The first collection of terms was published in June 2023 with a focus on photo catalysis. Our goal is to continuously extend the vocabulary to other areas of catalysis and related disciplines like chemical engineering or materials science.

Active172 weeks ago
Just
CC0-1.0

The HGVS Nomenclature is an internationally-recognized standard for the description of DNA, RNA and protein sequence variants. It is used to convey variants in clinical reports and to share variants in publications and databases. The HGVS Nomenclature is administered by the [HGVS Variant Nomenclature Committee (HVNC)](https://hgvs-nomenclature.org/stable/hvnc/) under the auspices of the [Human Genome Organization (HUGO)](https://hugo-int.org/).

Active133 weeks ago
Python
MIT

A vocabulary used in tandem with SHACL for representing node shapes

Active1553 weeks ago
HTML
NOASSERTION

The DCAT-AP conversion to a LinkML Schema is the intended point of truth for the DCAT-AP+ schema, but could be used alternatively as a LinkML representation of DCAT-AP for other Projects. It is a port of DCAT-AP to the LinkML world that is as faithful to the original as possible. This Persistent Identifier does not only provide the SHACL Shape, but could also be used as described [here](https://github.com/perma-id/w3id.org/tree/cecbc2e5f40d928f05ed5306d24fc60db0e7bb21/nfdi-de/dcat-ap-plus). DCAT-AP+ is a [LinkML](https://linkml.io/)-based extension of the [DCAT Application Profile 3.0](https://semiceu.github.io/DCAT-AP/releases/3.0.0/) that adds a provenance layer for describing how a dataset was generated and what it is about, using the [Starting Point Terms of PROV-O](https://www.w3.org/TR/prov-o/#description-starting-point-terms), the [QUDT ontology](https://www.qudt.org/), and [Dublin Core Terms](http://purl.org/dc/terms/).

Active113 weeks ago
Python
MIT

Ontology representation of the [International Committee on Taxonomy of Viruses (ICTV)](https://ictv.global/) for the [EVORA project](https://evora-project.eu/)

Active23 weeks ago
Python
Apache-2.0

This ontology describes sensors, actuators and observations, and related concepts. It does not describe domain concepts, time, locations, etc. these are intended to be included from other ontologies via OWL imports.

Active173 weeks ago
HTML

This is the Provenance Information for Materials Science (PRIMA) Ontology, version 3.0, aligned with PMDco v3 and based on BFO (Basic Formal Ontology). This complete module imports all PRIMA modules (core, data-analysis-lifecycle, dataset, experiment, and computational) in their v3.0 versions. [from https://purls.helmholtz-metadaten.de/prima/complete]

Active11 month ago
JavaScript
CC-BY-3.0

Some IDs may represent experiment sets, e.g. https://www.mavedb.org/#/experiment-sets/urn:mavedb:00000011 Others represent genomic regions (specifically deep mutational scans thereof) e.g. https://www.mavedb.org/#/experiment-sets/urn:mavedb:00000011-a

Active171 month ago
Python
AGPL-3.0

The Europeana Data Model (EDM) is aimed at being an integration medium for collecting, connecting and enriching the descriptions provided by Europeana data providers. The RDF vocabulary for http://www.europeana.eu/schemas/edm/ defines the elements introduced by EDM (as opposed to the ones EDM re-uses from other namespaces).

Active71 month ago
XSLT

An issue on the MONDO GitHub issue tracker

Active3111 month ago
Jupyter Notebook
CC-BY-4.0

Use this database to browse the CMECS classification and to get definitions for individual CMECS Units. This database contains the units that were published in the Coastal and Marine Ecological Classification Standard.

Active91 month ago
NOASSERTION

This ontology models classes and relationships describing deep learning networks, their component layers and activation functions, as well as potential biases.

Active591 month ago
Jupyter Notebook
NOASSERTION

This ontology is based on the SSN Ontology by the W3C Semantic Sensor Networks Incubator Group (SSN-XG), together with considerations from the W3C/OGC Spatial Data on the Web Working Group.

Active1651 month ago
HTML

MITE (Minimum Information about a Tailoring Enzyme) is a data repository and associated data standard designed to capture the reaction- and substrate-specificities of tailoring enzymes. Community-driven and fully expert-reviewed, it represents enzymatic reactions using reaction SMARTS and links to established resources such as UniProt, NCBI GenPept, Rhea, and MIBiG. MITE serves as a knowledgebase for enzyme and pathway annotation, in silico biosynthesis, and machine learning applications.

Active31 month ago
Python
CC0-1.0

A data model for managing information about chemical entities, ranging from atoms through molecules to complex mixtures.

Active231 month ago
Python
CC0-1.0

The gEAR portal is a website for visualization and analysis of multi-omic data both in public and private domains.

Active221 month ago
Jupyter Notebook
AGPL-3.0

METPO (Microbial Ecophysiological Trait and Phenotype Ontology) provides standardized terms for describing microbial phenotypes, growth characteristics, and culture conditions. It includes classes for growth media, temperature tolerances, pH tolerances, and relationships like "grows in" and "does not grow in".

Active11 month ago
Python
CC-BY-4.0
Active81 month ago
Makefile
NOASSERTION

Medical Subject Headings vocabulary is the set of predicates used in the MeSH RDF dump

Active811 month ago
Java

An Apache-based persistent URL (PURL) service

Active51 month ago
HTML
MIT

Darwin Core is a vocabulary standard for transmitting information about biodiversity. This document lists all terms in namespaces currently used in the vocabulary.

Active2521 month ago
Jinja
CC-BY-4.0