Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

672 of 6,565 resources

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This is a merge of pre-trained language models created using mergekit.

Idle418 months ago

From paper: "MolParser: End-to-end Visual Recognition of Molecule Structures in the Wild" (ICCV2025 Accept)

Idle08 months ago

MACE-MH-1 is a foundation machine-learning interatomic potential (MLIP) that bridges molecular, surface, and materials chemistry through cross-domain learning:

Idle08 months ago

Hulu-Med: A Transparent Generalist Model towards Holistic Medical Vision-Language Understanding

Idle12.3K8 months ago
Python

Large Language and Vision Assistant for bioMedicine (i.e., “LLaVA-Med”) is a large language and vision model trained using a curriculum learning method for adapting LLaVA to the biomedical domain. It is an open-source release intended for research use only to facilitate reproducibility of the…

Idle11.5K9 months ago
Python

MedQA Github porject: https://github.com/hussien/MedQA Read the detailed expermintal report here: https://github.com/hussien/MedQA/blob/main/report/MedQA.pdf

Idle1439 months ago

ChemFIE-BED is a sentence-transformers based on gbyuvd/chemselfies-base-bertmlm fine-tuned on around (for now) 2 million pairs of valid molecules' SELFIES (Krenn et al. 2020) taken from COCONUTDB (Sorokina et al. 2021) and ChemBL34 (Zdrazil et al. 2023).

Idle969 months ago
Python

GitHub homepage: Cell2Sentence GitHub

Idle2.1K9 months ago
Python
Idle763.8K9 months ago
Python

This model is a fine-tuned version of google/medgemma-4b-it adapted for binary mammogram classification on the OMAMA 256×256 dataset. The dataset consists of ~154k mammogram image slices (.npz) with metadata JSONs providing labels (NonCancer, Cancer).

Idle1510 months ago
Python

For a convenient overview and download list, visit our model page for this model.

Idle46810 months ago
Python

Tahoe-x1 is a family of perturbation-trained single-cell foundation models with up to 3 billion parameters, developed by Tahoe Therapeutics. Pretrained on 266 million single-cell transcriptomic profiles including the Tahoe-100M perturbation compendium, Tahoe-x1 achieves state-of-the-art performance…

Idle5910 months ago

BioCAP is a foundation model for biology organismal images. It is trained on TreeOfLife-10M with synthetic captions (TreeOfLife-10M-Captions) as supervision on the basis of a CLIP model (ViT-B/16) pre-trained by OpenAI. BioCAP achieves state-of-the-art performance on text-image retrieval tasks.

Idle27710 months ago

The Nucleotide Transformers are a collection of foundational language models that were pre-trained on DNA sequences from whole-genomes. Compared to other approaches, our models do not only integrate information from single reference genomes, but leverage DNA sequences from over 3,200 diverse human…

Idle14.1K10 months ago
Python

Specialized model for Species Entity Recognition - Species and organism names

Idle910 months ago

GeneJEPA is a Joint-Embedding Predictive Architecture (JEPA) trained for self-supervised representation learning on scRNA-seq. It uses a Perceiver-style encoder to handle sparse, high-dimensional gene count vectors and a Fourier-feature tokenizer for numerical tokenization.

Idle010 months ago

DermLIP is a vision-language model for dermatology, trained on the Derm1M dataset—the largest dermatological image-text corpus to date. This model variant (PanDerm-base-w-PubMed-256) utilizes domain-specific pretraining to deliver superior performance compared to other DermLIP variants..

Idle12910 months ago
Python

Hulu-Med: A Transparent Generalist Model towards Holistic Medical Vision-Language Understanding

Idle810 months ago

# Biomni-R0-32B-Preview This repo contains the weights of Biomni-R0-32B-Preview, a research preview of the series of biomedical AI agents trained by the Biomni team.

Idle2.7K10 months ago

InstaNovoPlus is a diffusion-based model for de novo peptide sequencing from mass spectrometry data. This model leverages multinomial diffusion for accurate, database-free peptide identification for large-scale proteomics experiments.

Idle2110 months ago

Typhoon-Si-Med-Thinking-4B is Southeast Asia’s first state-of-the-art, small, and efficient medical reasoning model, jointly developed by Typhoon (SCB 10X) and the Siriraj Informatics and Data Innovation Center (SiData+) at Siriraj Hospital, Mahidol University.

Idle5110 months ago

MedVAL-4B (medical text validator) is a language model fine-tuned to assess AI-generated medical text outputs at near physician-level reliability.

Idle20310 months ago
Python

This model is a lightweight model pre-trained on SELFIES (Self-Referencing Embedded Strings) representations of molecules. It is trained on 2.7M unique and valid molecules taken from COCONUTDB and ChemBL34, with 7.3M total generated masked examples.

Idle1411 months ago
Python

> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.

Idle3411 months ago
Python

> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.

Idle58311 months ago
Python

Website    🤖 7B Model    🤖 32B Model    MedEvalKit    Technical Report    Lingshu MCP

Idle1.6K11 months ago
Python

Website    🤖 7B Model    🤖 32B Model    MedEvalKit    Technical Report    Lingshu MCP

Idle4.1K11 months ago
Python

The Nucleotide Transformers are a collection of foundational language models that were pre-trained on DNA sequences from whole-genomes. Compared to other approaches, our models do not only integrate information from single reference genomes, but leverage DNA sequences from over 3,200 diverse human…

Idle2.9K11 months ago
Python

The Nucleotide Transformers are a collection of foundational language models that were pre-trained on DNA sequences from whole-genomes. Compared to other approaches, our models do not only integrate information from single reference genomes, but leverage DNA sequences from over 3,200 diverse human…

Idle17.9K11 months ago
Python

Evo 2 is a state of the art DNA language model for long context modeling and design. Evo 2 models DNA sequences at single-nucleotide resolution at up to 1 million base pair context length using the StripedHyena 2 architecture, using Savanna.

Idle011 months ago

# Model Card for Model ID PlantGFM is a genetic foundation model pre-trained on the complete genome sequences of 12 model plants, encompassing 108 billion nucleotides. Using the Hyena framework with 220 million parameters and a context length of 64K bp, PlantGFM models sequences at…

Idle7511 months ago
Idle4.6K11 months ago

NovoMolGen is a family of molecular foundation models trained on 1.5 billion ZINC-22 molecules with Llama architectures and FlashAttention. It achieves state-of-the-art performance on both unconstrained and goal-directed molecule generation tasks.

Idle40311 months ago

Palmyra-Med, a powerful LLM designed for healthcare

Idle5311 months ago
Python

中文版说明

Idle14711 months ago
Python

Neeto-1.0-8b is an openly released biomedical large language model (LLM) created by BYOL Academy to assist learners and practitioners with medical exam study, literature understanding, and structured clinical reasoning.

Idle7.7K11 months ago
Python
Idle5111 months ago
Python

This repository contains the official model of the paper A Unified Predictive and Generative Solution for Liquid Electrolyte Formulation.

Idle012 months ago

This is a ReactionT5 pre-trained to predict the products of reactions. You can use the demo here.

Idle2K1 year ago
Python

This is a ReactionT5 pre-trained to predict the reactants of reactions. You can use the demo here.

Idle1.7K1 year ago
Python

This repos contains the biomedicine MLLM developed from Qwen2.5-VL-3B-Instruct in our paper: On Domain-Adaptive Post-Training for Multimodal Large Language Models. The correspoding training dataset is in biomed-visual-instructions.

Idle1211 year ago
Python

# LAMAR LAMAR is a Foundation Language Model for RNA Regulation, which achieves better or comparable performance compared to baseline models in various RNA regulation tasks, helping to decipher the rules of RNA regulation.

Idle01 year ago

Specialized model for Chemical Entity Recognition - Identifies chemical compounds and substances in biomedical literature

Idle711 year ago
Python

Specialized model for Chemical Entity Recognition - Identifies chemical compounds and substances in biomedical literature

Idle104.1K1 year ago
Python

Specialized model for Chemical Entity Recognition - Chemical entities from the BC5CDR dataset

Idle258K1 year ago
Python

A specialized medical embedding model fine-tuned from Clinical ModernBERT using InfoNCE contrastive learning on PubMed title-abstract pairs.

Idle3.3K1 year ago
Python

JAMUN is a novel approach for generating conformational ensembles of protein structures, presented in the paper JAMUN: Bridging Smoothed Molecular Dynamics and Score-Based Learning for Conformational Ensembles.

Idle01 year ago