Find open-source science resources
A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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288 of 5,893 resources
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Lab-Rasool/RadImageNet
by Lab-RasoolThis repository contains pre-trained models from RadImageNet, a large-scale radiologic image dataset designed to facilitate transfer learning for medical imaging applications.
ibm-research/materials.smi-ted
by ibm-researchWelcome to IBM's series of large foundation models for sustainable materials. Our models span a variety of representations and modalities, including SMILES, SELFIES, 3D atom positions, 3D density grids, molecular graphs, and other formats.
zhihan1996/DNA_bert_3
by zhihan1996zhihan1996/DNA_bert_4
by zhihan1996zhihan1996/DNA_bert_5
by zhihan1996zhihan1996/DNA_bert_6
by zhihan1996SaltySander/MOSAIC
by SaltySandermicrosoft/NatureLM-8x7B
by microsoft# Model details ## Model description Nature Language Model (NatureLM) is a sequence-based science foundation model designed for scientific discovery. Pre-trained with data from multiple scientific domains, NatureLM offers a unified, versatile model that enables various applications including…
microsoft/NatureLM-8x7B-Inst
by microsoft# Model details ## Model description Nature Language Model (NatureLM) is a sequence-based science foundation model designed for scientific discovery. Pre-trained with data from multiple scientific domains, NatureLM offers a unified, versatile model that enables various applications including…
An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…
An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…
An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…
An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…
An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…
This model had been created as part of joint research of HUMADEX research group (https://www.linkedin.com/company/101563689/) and has received funding by the European Union Horizon Europe Research and Innovation Program project SMILE (grant number 101080923) and Marie Skłodowska-Curie Actions…
An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…
mathpluscode/CineMA
by mathpluscodeCineMA is a foundation model for Cine cardiac magnetic resonance (CMR) imaging based on Masked-Autoencoder. CineMA has been pre-trained on UK Biobank data and fine-tuned on multiple clinically relevant tasks such as ventricle and myocaridum segmentation, ejection fraction (EF) regression,…
Sisigoks/FloraSense
by SisigoksFloraSense is a fine-tuned Vision Transformer (ViT) model designed for accurate classification of plant species and flora-related imagery. It builds on top of the powerful google/vit-base-patch16-224 base model and is fine-tuned on the PlanterGARDENEDITION dataset curated by Sisigoks, which…
Using llama.cpp release b5466 for quantization.
Dans-PersonalityEngine-V1.3.0-24b Dans-PersonalityEngine-V1.3.0-24b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀…
Dans-PersonalityEngine-V1.2.0-24b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀ ⠀⢌⠀⠤⠀⢠⣞⣾⡗⠁⠀⠈⠁⢨⡼⠀⠀⠀⢀⠀⣀⡤⣄⠄⠈⢻⡇⠀⠐⣠⠜⠑⠁⠀⣀⡔⡿⠨⡄…
Unsloth Dynamic 2.0 achieves superior accuracy & outperforms other leading quants.
ibm-research/GP-MoLFormer-Uniq
by ibm-researchGP-MoLFormer is a class of models pretrained on SMILES string representations of 0.65-1.1B molecules from ZINC and PubChem. This repository is for the model pretrained on all the unique molecules from both datasets.
XformAI-india/qwen-0.6b-mentalhealth-support
by XformAI-indiaModel Repo: xformai/qwen-0.6b-mentalhealth-support Base Model: Qwen/Qwen-0.5B Task: Empathetic Conversational AI for mental health & emotional support Fine-Tuned By: XformAI
QIAIUNCC/EYE-Llama_gqa
by QIAIUNCC## Model Description EYE-Llama_gqa is a large language model specifically designed for ophthalmic question-answering (QA). It is built upon the Llama 2 architecture and fine-tuned on a the EYE-lit and EYE-QA+ dataset.
## Overview This project focuses on curating and modeling bioactivity data of small molecules targeting immune receptors. Using datasets from ImmtorLig_DB, we applied machine learning techniques to predict interactions between small molecules and immune receptors or cytokines, aiding drug discovery…
prov-gigapath/prov-gigapath
by prov-gigapathmedicalai/ClinicalBERT
by medicalaiThis model card describes the ClinicalBERT model, which was trained on a large multicenter dataset with a large corpus of 1.2B words of diverse diseases we constructed. We then utilized a large-scale corpus of EHRs from over 3 million patient records to fine tune the base language model.
Protein solubility is a critical factor in both pharmaceutical research and production processes, as it can significantly impact the quality and function of a protein. This is an example for finetuning ibm/biomed.omics.bl.sm-ted-458m for protein solubility prediction (binary classification) based…
prithivMLmods/Indian-Western-Food-34
by prithivMLmods!fffffff.png
PurvaTijare/PPTStab
by PurvaTijarePPTStab: Prediction and Designing of thermostable proteins with a desired melting temperature
mradermacher/Dans-PersonalityEngine-V1.2.0-24b-i1-GGUF
by mradermacherIf you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.
한국어 모델을 이용한 SapBERT(Self-alignment pretraining for BERT)입니다. 한·영 의료 용어 사전인 KOSTOM을 사용해 한국어 용어와 영어 용어를 정렬했습니다. 참고: SapBERT, Original Code
DOEJGI/GenomeOcean-4B
by DOEJGIThis is the base model of GenomeOcean-4B. It is trained with Causal Language Modeling (CLM) and uses a BPE tokenizer with 4096 tokens. It supports a maximum sequence length of 10240 tokens (~50kbp).
StanfordShahLab/llama-base-4096-clmbr
by StanfordShahLabsonglab/gpn-brassicales
by songlab# GPN trained on Arabidopsis thaliana and 7 other Brassicales See https://github.com/songlab-cal/gpn for more details.
BiomedCLIP is a biomedical vision-language foundation model that is pretrained on PMC-15M, a dataset of 15 million figure-caption pairs extracted from biomedical research articles in PubMed Central, using contrastive learning.
FremyCompany/BioLORD-2023
by FremyCompany# FremyCompany/BioLORD-2023 This model was trained using BioLORD, a new pre-training strategy for producing meaningful representations for clinical sentences and biomedical concepts.
Henrychur/MMedS-Llama-3-8B
by Henrychur# MMedS-Llama3 💻Github Repo 🖨️arXiv Paper
Accurate prediction of drug-target binding affinity is essential in the early stages of drug discovery. This is an example of finetuning ibm/biomed.omics.bl.sm-ted-400 the task. Prediction of binding affinities using pKd, the negative logarithm of the dissociation constant, which reflects the…
T-cell receptor (TCR) binding to immunogenic peptides (epitopes) presented by major histocompatibility complex (MHC) molecules is a critical mechanism in the adaptive immune system, essential for antigen recognition and triggering immune responses.
Drugs must satisfy stringent criteria for both efficacy and safety. This model predicts the likelihood of FDA approval for small-molecule drugs, represented using SMILES (Simplified Molecular Input Line Entry System) strings.
Drugs must satisfy stringent criteria for both efficacy and safety. This model predicts the likelihood of failure in clinical toxicity trials for small-molecule drugs, represented using SMILES (Simplified Molecular Input Line Entry System) strings.
Drugs targeting the central nervous system must meet stringent criteria for both efficacy and safety, including their ability to penetrate the blood-brain barrier (BBB). This model predicts the likelihood of small-molecule drugs crossing the BBB, a critical factor in CNS drug development.
Accurate prediction of drug-target binding affinity is essential in the early stages of drug discovery. Traditionally, binding affinities are measured through high-throughput screening experiments, which, while accurate, are resource-intensive and limited in their scalability to evaluate large sets…
ibm-research/biomed.omics.bl.sm.ma-ted-458m
by ibm-researchThe ibm/biomed.omics.bl.sm.ma-ted-458m model is a biomedical foundation model trained on over 2 billion biological samples across multiple modalities, including proteins, small molecules, and single-cell gene data. Designed for robust performance, it achieves state-of-the-art results over a variety…