Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

672 of 6,565 resources

Showing 551600

T-cell receptor (TCR) binding to immunogenic peptides (epitopes) presented by major histocompatibility complex (MHC) molecules is a critical mechanism in the adaptive immune system, essential for antigen recognition and triggering immune responses.

Idle441 year ago

Drugs must satisfy stringent criteria for both efficacy and safety. This model predicts the likelihood of FDA approval for small-molecule drugs, represented using SMILES (Simplified Molecular Input Line Entry System) strings.

Idle151 year ago

Drugs must satisfy stringent criteria for both efficacy and safety. This model predicts the likelihood of failure in clinical toxicity trials for small-molecule drugs, represented using SMILES (Simplified Molecular Input Line Entry System) strings.

Idle181 year ago

Drugs targeting the central nervous system must meet stringent criteria for both efficacy and safety, including their ability to penetrate the blood-brain barrier (BBB). This model predicts the likelihood of small-molecule drugs crossing the BBB, a critical factor in CNS drug development.

Idle231 year ago

Accurate prediction of drug-target binding affinity is essential in the early stages of drug discovery. Traditionally, binding affinities are measured through high-throughput screening experiments, which, while accurate, are resource-intensive and limited in their scalability to evaluate large sets…

Idle131 year ago

The ibm/biomed.omics.bl.sm.ma-ted-458m model is a biomedical foundation model trained on over 2 billion biological samples across multiple modalities, including proteins, small molecules, and single-cell gene data. Designed for robust performance, it achieves state-of-the-art results over a variety…

Idle2K1 year ago

### Welcome to Nidum! At Nidum, we believe in pushing the boundaries of innovation by providing advanced and unrestricted AI models for every application. Dive into our world of possibilities and experience the freedom of Nidum-Llama-3.2-3B-Uncensored, tailored to meet diverse needs with…

Idle4.3K1 year ago
Python

ProCyon-Full is a multimodal foundation model for protein phenotypes, which combines a large language model with protein encoders to support inputs of interleaved free text and proteins. This model is instruction-tuned using the full ProCyon-Instruct dataset.

Idle01 year ago

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle1.2K1 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle1921 year ago
Python

# Model Card for Model ID More code details can be found at Github: https://github.com/Incredible88/BioMistral-Clinical-7B ## How to use

Idle181 year ago

Boltz-1:

Idle01 year ago

Welcome to the repository for Nidum-Limitless-Gemma-2B-GGUF, an advanced language model that provides unrestricted and versatile responses across a wide range of topics. This version is designed for maximum flexibility, allowing you to run it on both CPU and GPU.

Idle2.4K1 year ago

We identified and fixed an issue related to a wrong permutation of some projections, which affects generation quality. To use the new model revision, please load as follows:

Idle2.8K1 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle5331 year ago
Python

This model aims to be a base template for new models. It has been generated using this raw template.

Idle1291 year ago
Python

This repository provides a simplified implementation for using the MedImageInsight model, an open-source medical imaging embedding model presented in the paper MedImageInsight: An Open-Source Embedding Model for General Domain Medical Imaging by Noel C. F. Codella et al.

Idle01 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-HIV-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle161 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-FREESOLV-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle121 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-QM7-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle111 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-BBBP-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle581 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-ESOL-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle101 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-CLINTOX-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle121 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-TOXCAST-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle81 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-LIPOPHILICITY-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image,…

Idle3481 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-TOX21-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle181 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-SIDER-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle131 year ago

# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-MUV-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…

Idle111 year ago

Dataset for paper "Teach Multimodal LLMs to Comprehend Electrocardiographic Images".

Idle1.6K1 year ago

The plant DNA large language models (LLMs) contain a series of foundation models based on different model architectures, which are pre-trained on various plant reference genomes. All the models have a comparable model size between 90 MB and 150 MB, BPE tokenizer is used for tokenization and 8000…

Idle41 year ago

Indus (previously known as nasa-smd-ibm-v0.1) is a RoBERTa-based, Encoder-only transformer model, domain-adapted for NASA Science Mission Directorate (SMD) applications. It's fine-tuned on scientific journals and articles relevant to NASA SMD, aiming to enhance natural language technologies like…

Idle551 year ago
Python

Indus-Retriever (nasa-smd-ibm-st-v2) is a Bi-encoder sentence transformer model, that is fine-tuned from nasa-smd-ibm-v0.1 encoder model. it is an updated version of nasa-smd-ibm-st with better performance (shown below). It's trained with 271 million examples along with a domain-specific dataset of…

Idle27.9K1 year ago
Python

license: mit language: - en metrics: - f1 tags: - medical

Idle691 year ago

MediFlow se trata de un modelo inicializado con xlnet-large-cased y adaptado con preguntas y especialidades para poder realizar Derivaciones Automatizadas en Servicios Hospitalarios. El dataset se puede encontrar de manera pública y se trata de MedDialog EN.

Idle61 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle3811 year ago
Python

> [!IMPORTANT] > Better using New version of ChemLLM! > AI4Chem/ChemLLM-7B-Chat-1.5-DPO or AI4Chem/ChemLLM-7B-Chat-1.5-SFT

Idle1.1K1 year ago
Python

Chemma-2B is a continually pretrained gemma-2b model for organic molecules. It is pretrained on 40B tokens covering 110M+ molecules from PubChem as well as their chemical properties (molecular weight, synthetic accessibility score, drug-likeness etc.) and similarities (Tanimoto distance between…

Idle471 year ago
Python

## Quick Start ```Python from transformers import AutoTokenizer, AutoModel

Idle381 year ago
Python

# Mistral-7B-DSM5 This model is fine-tuned from the Mistral-7b-Instruct-v0.2. We propose a method where an Instruct-Tuned language model first acquires knowledge in a specific domain through RAG (Retrieval-Augmented Generation) techniques.

Idle91 year ago

!alt text

Idle72 years ago
Stale71.9K2 years ago

TinyDNABERT is a specialized deep learning model designed for understanding the language of DNA and performing DNA sequence classification tasks. This model is a compact and efficient version of the DNABERT model, optimized to reduce memory usage while maintaining high performance.

Stale2372 years ago
Stale02 years ago

ChemFIE-SA is a BERT-like sequence classifier for predicting synthesis accessibility given a SELFIES string of a compound, fine-tuned from gbyuvd/chemselfies-base-bertmlm on DeepSA's expanded dataset from Wang et al. 2023.

Stale132 years ago
Python

This model is a BERT-like sequence classifier for 221 human protein drug targets, fine-tuned from gbyuvd/chemselfies-base-bertmlm on a dataset derived ChemBL34 (Zdrazil et al. 2023). It predicts potential drug targets using chemical structures represented as SELFIES (Self-Referencing Embedded…

Stale192 years ago
Python

The Mistral-DNA-v1-138M-bacteria Large Language Model (LLM) is a pretrained generative DNA text model with 17.31M parameters x 8 experts = 138.5M parameters. It is derived from Mistral-7B-v0.1 model, which was simplified for DNA: the number of layers and the hidden size were reduced.

Stale162 years ago
Python

Model Card for "medllama" ---------------------------

Stale152 years ago
Python

This is a ReactionT5 pre-trained to predict the products of reactions.

Stale1162 years ago
Python

Universal Cell Embeddings (UCE) is a foundation model designed for single-cell RNA sequencing data analysis. UCE generates a universal representation of cells that captures the molecular diversity across different cell types, tissues, and species.

Stale142 years ago

!image/png

Stale7.9K2 years ago
Python