Find open-source science resources
A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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T-cell receptor (TCR) binding to immunogenic peptides (epitopes) presented by major histocompatibility complex (MHC) molecules is a critical mechanism in the adaptive immune system, essential for antigen recognition and triggering immune responses.
Drugs must satisfy stringent criteria for both efficacy and safety. This model predicts the likelihood of FDA approval for small-molecule drugs, represented using SMILES (Simplified Molecular Input Line Entry System) strings.
Drugs must satisfy stringent criteria for both efficacy and safety. This model predicts the likelihood of failure in clinical toxicity trials for small-molecule drugs, represented using SMILES (Simplified Molecular Input Line Entry System) strings.
Drugs targeting the central nervous system must meet stringent criteria for both efficacy and safety, including their ability to penetrate the blood-brain barrier (BBB). This model predicts the likelihood of small-molecule drugs crossing the BBB, a critical factor in CNS drug development.
Accurate prediction of drug-target binding affinity is essential in the early stages of drug discovery. Traditionally, binding affinities are measured through high-throughput screening experiments, which, while accurate, are resource-intensive and limited in their scalability to evaluate large sets…
ibm-research/biomed.omics.bl.sm.ma-ted-458m
by ibm-researchThe ibm/biomed.omics.bl.sm.ma-ted-458m model is a biomedical foundation model trained on over 2 billion biological samples across multiple modalities, including proteins, small molecules, and single-cell gene data. Designed for robust performance, it achieves state-of-the-art results over a variety…
### Welcome to Nidum! At Nidum, we believe in pushing the boundaries of innovation by providing advanced and unrestricted AI models for every application. Dive into our world of possibilities and experience the freedom of Nidum-Llama-3.2-3B-Uncensored, tailored to meet diverse needs with…
mims-harvard/ProCyon-Full
by mims-harvardProCyon-Full is a multimodal foundation model for protein phenotypes, which combines a large language model with protein encoders to support inputs of interleaved free text and proteins. This model is instruction-tuned using the full ProCyon-Instruct dataset.
mradermacher/Bio-Medical-Llama-3.1-8B-i1-GGUF
by mradermacherIf you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.
mradermacher/Breeze-Petro-7B-Instruct-v1-i1-GGUF
by mradermacherIf you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.
# Model Card for Model ID More code details can be found at Github: https://github.com/Incredible88/BioMistral-Clinical-7B ## How to use
Welcome to the repository for Nidum-Limitless-Gemma-2B-GGUF, an advanced language model that provides unrestricted and versatile responses across a wide range of topics. This version is designed for maximum flexibility, allowing you to run it on both CPU and GPU.
togethercomputer/evo-1-131k-base
by togethercomputerWe identified and fixed an issue related to a wrong permutation of some projections, which affects generation quality. To use the new model revision, please load as follows:
mradermacher/Hyperion-2.0-Mistral-7B-i1-GGUF
by mradermacherIf you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.
peteparker456/medical_diagnosis_llama2
by peteparker456This model aims to be a base template for new models. It has been generated using this raw template.
lion-ai/MedImageInsights
by lion-aiThis repository provides a simplified implementation for using the MedImageInsight model, an open-source medical imaging embedding model presented in the paper MedImageInsight: An Open-Source Embedding Model for General Domain Medical Imaging by Noel C. F. Codella et al.
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-HIV-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-FREESOLV-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-QM7-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-BBBP-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-ESOL-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-CLINTOX-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-TOXCAST-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-LIPOPHILICITY-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image,…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-TOX21-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-SIDER-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
# ibm/biomed.sm.mv-te-84m-MoleculeNet-ligand_scaffold-MUV-101 biomed.sm.mv-te-84m is a multimodal biomedical foundation model for small molecules created using MMELON (Multi-view Molecular Embedding with Late Fusion), a flexible approach to aggregate multiple views (sequence, image, graph) of…
PULSE-ECG/PULSE-7B
by PULSE-ECGDataset for paper "Teach Multimodal LLMs to Comprehend Electrocardiographic Images".
zhangtaolab/plant-dnabert-6mer
by zhangtaolabThe plant DNA large language models (LLMs) contain a series of foundation models based on different model architectures, which are pre-trained on various plant reference genomes. All the models have a comparable model size between 90 MB and 150 MB, BPE tokenizer is used for tokenization and 8000…
nasa-impact/nasa-smd-ibm-v0.1
by nasa-impactIndus (previously known as nasa-smd-ibm-v0.1) is a RoBERTa-based, Encoder-only transformer model, domain-adapted for NASA Science Mission Directorate (SMD) applications. It's fine-tuned on scientific journals and articles relevant to NASA SMD, aiming to enhance natural language technologies like…
nasa-impact/nasa-smd-ibm-st-v2
by nasa-impactIndus-Retriever (nasa-smd-ibm-st-v2) is a Bi-encoder sentence transformer model, that is fine-tuned from nasa-smd-ibm-v0.1 encoder model. it is an updated version of nasa-smd-ibm-st with better performance (shown below). It's trained with 271 million examples along with a domain-specific dataset of…
QuantFactory/MentaLLaMA-chat-7B-GGUF
by QuantFactorylicense: mit language: - en metrics: - f1 tags: - medical
digitalhealth-healthyliving/MediFlow
by digitalhealth-healthylivingMediFlow se trata de un modelo inicializado con xlnet-large-cased y adaptado con preguntas y especialidades para poder realizar Derivaciones Automatizadas en Servicios Hospitalarios. El dataset se puede encontrar de manera pública y se trata de MedDialog EN.
mradermacher/Palmyra-Med-70B-GGUF
by mradermacherIf you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.
> [!IMPORTANT] > Better using New version of ChemLLM! > AI4Chem/ChemLLM-7B-Chat-1.5-DPO or AI4Chem/ChemLLM-7B-Chat-1.5-SFT
yerevann/chemma-2b
by yerevannChemma-2B is a continually pretrained gemma-2b model for organic molecules. It is pretrained on 40B tokens covering 110M+ molecules from PubChem as well as their chemical properties (molecular weight, synthetic accessibility score, drug-likeness etc.) and similarities (Tanimoto distance between…
qiuhuachuan/PsyChat
by qiuhuachuan## Quick Start ```Python from transformers import AutoTokenizer, AutoModel
chillymiao/Mistral-7B-DSM5
by chillymiao# Mistral-7B-DSM5 This model is fine-tuned from the Mistral-7b-Instruct-v0.2. We propose a method where an Instruct-Tuned language model first acquires knowledge in a specific domain through RAG (Retrieval-Augmented Generation) techniques.
fabihamakhdoomi/TinyDNABERT
by fabihamakhdoomiTinyDNABERT is a specialized deep learning model designed for understanding the language of DNA and performing DNA sequence classification tasks. This model is a compact and efficient version of the DNABERT model, optimized to reduce memory usage while maintaining high performance.
heartwise/DeepCoro
by heartwiseChemFIE-SA is a BERT-like sequence classifier for predicting synthesis accessibility given a SELFIES string of a compound, fine-tuned from gbyuvd/chemselfies-base-bertmlm on DeepSA's expanded dataset from Wang et al. 2023.
This model is a BERT-like sequence classifier for 221 human protein drug targets, fine-tuned from gbyuvd/chemselfies-base-bertmlm on a dataset derived ChemBL34 (Zdrazil et al. 2023). It predicts potential drug targets using chemical structures represented as SELFIES (Self-Referencing Embedded…
RaphaelMourad/Mistral-DNA-v1-138M-bacteria
by RaphaelMouradThe Mistral-DNA-v1-138M-bacteria Large Language Model (LLM) is a pretrained generative DNA text model with 17.31M parameters x 8 experts = 138.5M parameters. It is derived from Mistral-7B-v0.1 model, which was simplified for DNA: the number of layers and the hidden size were reduced.
tmberooney/medllama-merged
by tmberooneyModel Card for "medllama" ---------------------------
sagawa/ReactionT5v1-forward
by sagawaThis is a ReactionT5 pre-trained to predict the products of reactions.
minwoosun/uce-100m
by minwoosunUniversal Cell Embeddings (UCE) is a foundation model designed for single-cell RNA sequencing data analysis. UCE generates a universal representation of cells that captures the molecular diversity across different cell types, tissues, and species.