Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

15 of 6,223 resources

Open-source AI workbench for scientific research that automates the full research loop — literature review, hypothesis generation, code writing, experiment execution, database querying, and report writing — with 290+ skills, specialized research agents, and a browser-based workspace (1453+ stars, Apache 2.0, 2026)

Active1.8K2 days ago
TypeScript
Apache-2.0

Local-first, open-source AI workbench for scientists — an open alternative to Claude Science (by ai4s-research, maintainers of this list; TypeScript, MIT, 2026)

Active856 days ago
TypeScript
NOASSERTION

Offline-first scientific writing workspace powered by Claude, integrating LaTeX, Python, and 100+ scientific skills with local execution, Zotero integration, and privacy-focused design (2026)

Active1.7K1 week ago
TypeScript
MIT

Multi-type data labeling and annotation tool

Active27.7K1 week ago
TypeScript
Apache-2.0

A large RDF store built from American governmental data. This semantic space has a mixture of direct terms and subspaces.

Active312 weeks ago
TypeScript
Apache-2.0

Research agent system deeply integrated with Zotero supporting Agent Mode, skills, multi-model backends (OpenAI-compatible, Claude Code, WebChat, Codex), and MinerU PDF parsing for literature Q&A, summarization, figure inspection, and source comparison (1.3K+ stars, 2026)

Active2.1K2 weeks ago
TypeScript
AGPL-3.0

First system progressively surpassing human SOTA on frontier AI tasks (183.7%, 1.9%, 7.9% improvements), month-long autonomous discovery with 20,000+ GPU hours

Active3.1K3 weeks ago
TypeScript
Apache-2.0

An interactive structure/property explorer for materials and molecules.

Active1781 month ago
TypeScript
BSD-3-Clause

Self-evolving AI research colleague built on OpenClaw with 285+ runtime-adaptive skills across 28+ disciplines, persistent cross-session research memory, and zero-hallucination citation protocols; agent autonomously writes new SKILL.md files based on research patterns without redeployment (828+ stars, MIT License, 2026)

Active8291 month ago
TypeScript
MIT

A RDF vocabulary for OER content on the web.

Active221 month ago
TypeScript
MIT

Standalone browser-based Gene Ontology network viewer for exploring, filtering, searching, and exporting GO term and gene annotation neighborhoods from locally preprocessed GO OBO and GAF data.

Active01 month ago
TypeScript
MIT

2D interactive visualization in Jupyter.

Active3.7K2 months ago
TypeScript
Apache-2.0

Classic open-source plugin for document Q&A and summarization within Zotero

Active7.2K2 months ago
TypeScript
AGPL-3.0

Web application for LLM-assisted manuscript review and annotation

Idle11 year ago
TypeScript
MIT

Point and click, cross platform suite for analysing and visualizing next-generation sequencing datasets.

Stale173 years ago
TypeScript
GPL-3.0