Find open-source science resources
A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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470 of 7,050 resources
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Taykhoom/Helix-mRNA
by TaykhoomMinimal HuggingFace port of Helix-mRNA -- a hybrid Mamba2 / attention language model for full-length mRNA, trained with next-token prediction on single-nucleotide tokens with a codon-start marker.
insilicomedicine/longevity-llm
by insilicomedicineA domain-adapted Qwen3.5-9B for aging and longevity biology. L-LLM is the result of continued pretraining + supervised fine-tuning + a reasoning-augmented continuation pass on a multi-domain corpus spanning clinical aging, epigenomics, transcriptomics, proteomics, and genetics.
aigensciences/BioGravity-Inst
by aigensciencesBioGravity-Inst is a biomedical instruction model from AIGEN Sciences, Inc., developed from the Gravity 30B-A5B family. It is intended for biomedical research in the Biomni A1 environment, including question answering, evidence gathering, computation, and tool-assisted analysis.
lighteternal/biodecision-v2-4b
by lighteternalA System-1 decision model for biomedicine, pharma and clinical trials. It reads a source, a question and a set of possible answers, and returns a calibrated probability for each answer in one forward pass, with no generated text.
athanzli/MicroGlot
by athanzliA taxonomy-informed sparse DNA foundation model for microbial genomics.
drzo/ESMC-6B
by drzoESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
For a convenient overview and download list, visit our model page for this model.
For a convenient overview and download list, visit our model page for this model.
Aquiles-ai/Chargaff-Tokenizer
by Aquiles-aiByte-level BPE tokenizer for Chargaff, our DNA prediction model. No training, no merges: 1 token per UTF-8 byte.
UniParser/MolParser-Mobile-V2
by UniParser💻 GitHub | 📘 E-SMILES 2.0 Spec | 📄 Report | 🚀 Demo
Soilytix/LOAM-624M
by SoilytixGaolaboratory/iona-denoise-50m
by Gaolaboratoryiona-denoise-50m scores every peak of a tandem mass spectrum (MS/MS) as signal or noise. It is the Iona 50m encoder with a per-peak classification head, fine-tuned for noise-peak detection.
Gaolaboratory/iona-denoise-400m
by Gaolaboratoryiona-denoise-400m scores every peak of a tandem mass spectrum (MS/MS) as signal or noise. It is the Iona 400m encoder with a per-peak classification head, fine-tuned for noise-peak detection.
Gaolaboratory/iona-denoise-200m
by Gaolaboratoryiona-denoise-200m scores every peak of a tandem mass spectrum (MS/MS) as signal or noise. It is the Iona 200m encoder with a per-peak classification head, fine-tuned for noise-peak detection.
Gaolaboratory/iona-denoise-100m
by Gaolaboratoryiona-denoise-100m scores every peak of a tandem mass spectrum (MS/MS) as signal or noise. It is the Iona 100m encoder with a per-peak classification head, fine-tuned for noise-peak detection.
Three genomic foundation models, packaged together for local inference on Apple silicon.
Gaolaboratory/iona-base-400m
by GaolaboratoryIona is a transformer encoder foundation model for tandem mass spectra (MS/MS). It treats each centroided peak as a token and learns how peaks relate to each other through a per-head attention bias over the signed m/z difference (Δm/z) between every pair of peaks.
Gaolaboratory/iona-base-200m
by GaolaboratoryIona is a transformer encoder foundation model for tandem mass spectra (MS/MS). It treats each centroided peak as a token and learns how peaks relate to each other through a per-head attention bias over the signed m/z difference (Δm/z) between every pair of peaks.
Gaolaboratory/iona-base-100m
by GaolaboratoryIona is a transformer encoder foundation model for tandem mass spectra (MS/MS). It treats each centroided peak as a token and learns how peaks relate to each other through a per-head attention bias over the signed m/z difference (Δm/z) between every pair of peaks.
Gaolaboratory/iona-base-50m
by GaolaboratoryIona is a transformer encoder foundation model for tandem mass spectra (MS/MS). It treats each centroided peak as a token and learns how peaks relate to each other through a per-head attention bias over the signed m/z difference (Δm/z) between every pair of peaks.
FreedomIntelligence/HuatuoGPT-3-27B
by FreedomIntelligence🩺 HuatuoGPT-3-27B 🏠 GitHub | 📄 Paper
FreedomIntelligence/HuatuoGPT-3-9B
by FreedomIntelligence🩺 HuatuoGPT-3-9B 🏠 GitHub | 📄 Paper
FreedomIntelligence/HuatuoGPT-3-Grader-8B
by FreedomIntelligenceHuatuoGPT-3-Grader-8B GitHub | Paper
Kentucky-Open-Science/KOS-V5-Instruct
by Kentucky-Open-ScienceDeveloped by
Ultra-fast extraction of predefined clinical variables from free-text clinical notes.
This model card provides an overview of the intended use of the ESMC SAE models and examples of how to access them, but it does not have a specific model or model weights. To access each SAE model collection, use the links below:
The ESMC scaling-study checkpoints are being released to support reproducibility of the findings in our paper, please refer to the paper and github for details. Please use the ESMC model for research work. ESMC is a state-of-the-art protein language model trained on billions of protein sequences…
The ESMC scaling-study checkpoints are being released to support reproducibility of the findings in our paper, please refer to the paper and github for details. Please use the ESMC model for research work. ESMC is a state-of-the-art protein language model trained on billions of protein sequences…
The ESMC scaling-study checkpoints are being released to support reproducibility of the findings in our paper, please refer to the paper and github for details. Please use the ESMC model for research work. ESMC is a state-of-the-art protein language model trained on billions of protein sequences…
biohub/ESMC-6B
by biohubESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
biohub/ESMC-600M
by biohubESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
biohub/ESMC-300M
by biohubESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
biohub/ESMFold2
by biohubESMFold2 is a state-of-the-art model for protein structure prediction and design that defines a new frontier for speed and accuracy. The model predicts high-resolution, all-atom 3D protein structures directly from amino acid sequences, with optional multiple sequence alignment (MSA) input for…
biohub/ESMFold2-Fast
by biohubESMFold2 is a state-of-the-art model for protein structure prediction and design that defines a new frontier for speed and accuracy. The model predicts high-resolution, all-atom 3D protein structures directly from amino acid sequences, with optional multiple sequence alignment (MSA) input for…
scrc-dnai/DNT-8M-CPL-SMP
by scrc-dnaiscrc-dnai/DNT-100M_PRE-CPL-2e4
by scrc-dnaishreyansh12183/olmo2-7b-biomed-chem
by shreyansh12183A domain-adapted small language model specialized for molecular conformation analysis, computational biochemistry, and pharmacology reasoning.
Aquiles-ai/Evo2-7B
by Aquiles-aiEvo2-7B (Transformers port)
Aquiles-ai/Evo2-1B-Base
by Aquiles-aiEvo2-1B-Base (Transformers port)
ctheodoris/Geneformer
by ctheodoris# Geneformer Geneformer is a foundational transformer model pretrained on a large-scale corpus of human single cell transcriptomes to enable context-aware predictions in settings with limited data in network biology.
shikunpunk/ask-dao
by shikunpunk> ⚠️ 重要:本仓库的 adapter 历史上因 PeftModel.frompretrained 双重包装导致 key 嵌套错误。 > 旧版本里 PeftModel.frompretrained 加载会"Found missing adapter keys"并静默丢弃全部权重, > 模型实际退化为 base Qwen2.5-3B-Instruct。 > 现在本仓库的 adapter_model.safetensors 已重新打包为标准深度 8(504/504 keys 命中),可被正确加载。 > 验证方式:见 shikunpunk/ask-dao-v0.3 仓库里 "Holdout…
shikunpunk/ask-dao-v0.2-2ep
by shikunpunk知识发现机器 —— 从生物医学论文推断「作者没有明说」的开放科学问题
Aurigene-AI/ChemFM-1B
by Aurigene-AISee the upstream model card for full details, training data and citation.
learning-unit/L1-30B-A5B
by learning-unitL1-30B-A5B is the Korean-locale medical foundation model from Lunit and Lunit Consortium. It is the 30B member of the L1 family, post-trained directly from Gravity-30B-A5B-Base, a sparse Mixture-of-Experts model developed by Trillion Labs and the Lunit Consortium.
UniParser/MolParser-Mobile
by UniParser💻 Github | 📄 Report | 🚀 Demo
mradermacher/Nidum-Gemma-2B-Uncensored-GGUF
by mradermacherFor a convenient overview and download list, visit our model page for this model.