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A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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32 of 6,223 resources
doctolib-lab/doctobert-fr-base
by doctolib-lab🤗 Blog | 📄 Paper | 💻 Code | 🌐 FineMed | 🩺 DoctoBERT
divyeshkamalanaban/nucleotide-transformer-2.5b-multi-species-NF4-Q4
by divyeshkamalanabanThis model is an NF4 (Normal Float 4-bit) quantized version of the base model InstaDeepAI/nucleotide-transformer-2.5b-multi-species. The checkpoint was quantized using the BitsAndBytes library with double quantization enabled and BF16 computation.
biohub/ESMC-6B
by biohubESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
biohub/ESMC-600M
by biohubESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
biohub/ESMC-300M
by biohubESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…
ctheodoris/Geneformer
by ctheodoris# Geneformer Geneformer is a foundational transformer model pretrained on a large-scale corpus of human single cell transcriptomes to enable context-aware predictions in settings with limited data in network biology.
macwiatrak/bacformer-large-masked-MAG
by macwiatrak- 2025-05-15: We identified a bug in the Bacformer Large code on HuggingFace which resulted in a significant drop in the quality of the output embeddings. This is now fixed, but if you downloaded or cached the model before this date, re-download and use the latest model revision before running…
- 2025-05-15: We identified a bug in the Bacformer Large code on HuggingFace which resulted in a significant drop in the quality of the output embeddings. This is now fixed, but if you downloaded or cached the model before this date, re-download and use the latest model revision before running…
InstaDeepAI/NTv3_100M_post
by InstaDeepAIInstaDeepAI/NTv3_650M_pre
by InstaDeepAI## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.
## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology. This model version was continually pretrained on ~14 million cancer transcriptomes…
## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.
## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.
This model is a lightweight model pre-trained on SELFIES (Self-Referencing Embedded Strings) representations of molecules. It is trained on 2.7M unique and valid molecules taken from COCONUTDB and ChemBL34, with 7.3M total generated masked examples.
nvidia/AMPLIFY_350M
by nvidia> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.
nvidia/AMPLIFY_120M
by nvidia> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.
The Nucleotide Transformers are a collection of foundational language models that were pre-trained on DNA sequences from whole-genomes. Compared to other approaches, our models do not only integrate information from single reference genomes, but leverage DNA sequences from over 3,200 diverse human…
zhihan1996/DNA_bert_3
by zhihan1996zhihan1996/DNA_bert_4
by zhihan1996zhihan1996/DNA_bert_5
by zhihan1996zhihan1996/DNA_bert_6
by zhihan1996medicalai/ClinicalBERT
by medicalaiThis model card describes the ClinicalBERT model, which was trained on a large multicenter dataset with a large corpus of 1.2B words of diverse diseases we constructed. We then utilized a large-scale corpus of EHRs from over 3 million patient records to fine tune the base language model.
songlab/gpn-brassicales
by songlab# GPN trained on Arabidopsis thaliana and 7 other Brassicales See https://github.com/songlab-cal/gpn for more details.
nasa-impact/nasa-smd-ibm-v0.1
by nasa-impactIndus (previously known as nasa-smd-ibm-v0.1) is a RoBERTa-based, Encoder-only transformer model, domain-adapted for NASA Science Mission Directorate (SMD) applications. It's fine-tuned on scientific journals and articles relevant to NASA SMD, aiming to enhance natural language technologies like…
InstaDeepAI/agro-nucleotide-transformer-1b
by InstaDeepAI## Model Overview AgroNT is a DNA language model trained on primarily edible plant genomes. More specifically, AgroNT uses the transformer architecture with self-attention and a masked language modeling objective to leverage highly available genotype data from 48 different plant speices to learn…
AmelieSchreiber/esm_interact
by AmelieSchreiberThis model was finetuned on concatenated pairs of interacting proteins in much the same way as PepMLM. It is meant to generate interaction partners for proteins using the masked language modeling capabilities of ESM-2. The model is not well tested, so use with caution.
This is a Japanese RoBERTa base model pre-trained on academic articles in medical sciences collected by Japan Science and Technology Agency (JST).
In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.
Dr-BERT/DrBERT-4GB
by Dr-BERTIn recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.
Dr-BERT/DrBERT-7GB
by Dr-BERTIn recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.
Deep learning for chemistry and materials science remains a novel field with lots of potiential. However, the popularity of transfer learning based methods in areas such as NLP and computer vision have not yet been effectively developed in computational chemistry + machine learning.