Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

32 of 6,223 resources

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Active4601 week ago
Python

This model is an NF4 (Normal Float 4-bit) quantized version of the base model InstaDeepAI/nucleotide-transformer-2.5b-multi-species. The checkpoint was quantized using the BitsAndBytes library with double quantization enabled and BF16 computation.

Active533 weeks ago
Python

ESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…

Active1.3M1 month ago
Python

ESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…

Active467.8K1 month ago
Python

ESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…

Active10.3K1 month ago
Python

# Geneformer Geneformer is a foundational transformer model pretrained on a large-scale corpus of human single cell transcriptomes to enable context-aware predictions in settings with limited data in network biology.

Active6.1K1 month ago
Python

- 2025-05-15: We identified a bug in the Bacformer Large code on HuggingFace which resulted in a significant drop in the quality of the output embeddings. This is now fixed, but if you downloaded or cached the model before this date, re-download and use the latest model revision before running…

Active8K1 month ago
Python

- 2025-05-15: We identified a bug in the Bacformer Large code on HuggingFace which resulted in a significant drop in the quality of the output embeddings. This is now fixed, but if you downloaded or cached the model before this date, re-download and use the latest model revision before running…

Active5471 month ago
Python
Active10.8K4 months ago
Python
Active6.5K4 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Idle326 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology. This model version was continually pretrained on ~14 million cancer transcriptomes…

Idle166 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Idle316 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Idle176 months ago
Python

This model is a lightweight model pre-trained on SELFIES (Self-Referencing Embedded Strings) representations of molecules. It is trained on 2.7M unique and valid molecules taken from COCONUTDB and ChemBL34, with 7.3M total generated masked examples.

Idle19 months ago
Python

> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.

Idle349 months ago
Python

> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.

Idle5839 months ago
Python

The Nucleotide Transformers are a collection of foundational language models that were pre-trained on DNA sequences from whole-genomes. Compared to other approaches, our models do not only integrate information from single reference genomes, but leverage DNA sequences from over 3,200 diverse human…

Idle16.8K9 months ago
Python
Idle2K1 year ago
Python
Idle9661 year ago
Python
Idle9431 year ago
Python
Idle6.9K1 year ago
Python

This model card describes the ClinicalBERT model, which was trained on a large multicenter dataset with a large corpus of 1.2B words of diverse diseases we constructed. We then utilized a large-scale corpus of EHRs from over 3 million patient records to fine tune the base language model.

Idle21.2K1 year ago
Python

# GPN trained on Arabidopsis thaliana and 7 other Brassicales See https://github.com/songlab-cal/gpn for more details.

Idle1.6K1 year ago
Python

Indus (previously known as nasa-smd-ibm-v0.1) is a RoBERTa-based, Encoder-only transformer model, domain-adapted for NASA Science Mission Directorate (SMD) applications. It's fine-tuned on scientific journals and articles relevant to NASA SMD, aiming to enhance natural language technologies like…

Idle551 year ago
Python

## Model Overview AgroNT is a DNA language model trained on primarily edible plant genomes. More specifically, AgroNT uses the transformer architecture with self-attention and a masked language modeling objective to leverage highly available genotype data from 48 different plant speices to learn…

Idle4.2K1 year ago
Python

This model was finetuned on concatenated pairs of interacting proteins in much the same way as PepMLM. It is meant to generate interaction partners for proteins using the masked language modeling capabilities of ESM-2. The model is not well tested, so use with caution.

Stale82 years ago
Python

This is a Japanese RoBERTa base model pre-trained on academic articles in medical sciences collected by Japan Science and Technology Agency (JST).

Stale1463 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

Stale433 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

Stale923 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

Stale1.5K3 years ago
Python

Deep learning for chemistry and materials science remains a novel field with lots of potiential. However, the popularity of transfer learning based methods in areas such as NLP and computer vision have not yet been effectively developed in computational chemistry + machine learning.

Stale128.3K5 years ago
Python