Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

26 of 5,893 resources

ESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…

Active614.4K6 days ago
Python

ESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…

Active3.5K6 days ago
Python

ESMC is a state-of-the-art protein language model that has learned the rules of protein biology from training on billions of protein sequences. ESMC provides representations of proteins enabling novel AI applications from therapeutic protein engineering to unlocking basic insights into protein…

Active2.8K1 week ago
Python

# Geneformer Geneformer is a foundational transformer model pretrained on a large-scale corpus of human single cell transcriptomes to enable context-aware predictions in settings with limited data in network biology.

Active8.9K2 weeks ago
Python

- 2025-05-15: We identified a bug in the Bacformer Large code on HuggingFace which resulted in a significant drop in the quality of the output embeddings. This is now fixed, but if you downloaded or cached the model before this date, re-download and use the latest model revision before running…

Active8K3 weeks ago
Python

- 2025-05-15: We identified a bug in the Bacformer Large code on HuggingFace which resulted in a significant drop in the quality of the output embeddings. This is now fixed, but if you downloaded or cached the model before this date, re-download and use the latest model revision before running…

Active5473 weeks ago
Python
Active6.5K3 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Active325 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology. This model version was continually pretrained on ~14 million cancer transcriptomes…

Active165 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Active315 months ago
Python

## Description: Geneformer is a foundational transformer model pretrained on a large-scale corpus of single-cell transcriptomes to enable context-specific predictions in settings with limited data in network biology.

Active175 months ago
Python

This model is a lightweight model pre-trained on SELFIES (Self-Referencing Embedded Strings) representations of molecules. It is trained on 2.7M unique and valid molecules taken from COCONUTDB and ChemBL34, with 7.3M total generated masked examples.

Idle68 months ago
Python

> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.

Idle348 months ago
Python

> [!NOTE] > This model has been optimized using NVIDIA's TransformerEngine > library. Slight numerical differences may be observed between the original model and the optimized > model. For instructions on how to install TransformerEngine, please refer to the > official documentation.

Idle5838 months ago
Python
Idle2.3K11 months ago
Python
Idle73811 months ago
Python
Idle72911 months ago
Python
Idle6.2K11 months ago
Python

This model card describes the ClinicalBERT model, which was trained on a large multicenter dataset with a large corpus of 1.2B words of diverse diseases we constructed. We then utilized a large-scale corpus of EHRs from over 3 million patient records to fine tune the base language model.

Idle21.6K1 year ago
Python

# GPN trained on Arabidopsis thaliana and 7 other Brassicales See https://github.com/songlab-cal/gpn for more details.

Idle3461 year ago
Python

This model was finetuned on concatenated pairs of interacting proteins in much the same way as PepMLM. It is meant to generate interaction partners for proteins using the masked language modeling capabilities of ESM-2. The model is not well tested, so use with caution.

Stale32 years ago
Python

This is a Japanese RoBERTa base model pre-trained on academic articles in medical sciences collected by Japan Science and Technology Agency (JST).

Stale1462 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

Stale1703 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

Stale3213 years ago
Python

In recent years, pre-trained language models (PLMs) achieve the best performance on a wide range of natural language processing (NLP) tasks. While the first models were trained on general domain data, specialized ones have emerged to more effectively treat specific domains.

Stale1.5K3 years ago
Python

Deep learning for chemistry and materials science remains a novel field with lots of potiential. However, the popularity of transfer learning based methods in areas such as NLP and computer vision have not yet been effectively developed in computational chemistry + machine learning.

Stale276.9K5 years ago
Python