Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

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sBEE is a novel metric designed to robustly evaluate batch mixing in single-cell RNA sequencing (scRNA-seq) data. It assesses integration quality by combining local neighborhood composition and cross-batch distance relationships to provide stable benchmarking across diverse data characteristics.

Active02 months ago
Python

spVIPES is a probabilistic framework used for single-cell RNA-sequencing batch correction, designed to decompose unpaired datasets with nonmatching features into shared (conserved) and private (dataset-specific) cellular representations.

Idle48 months ago
Python
BSD-3-Clause

MitoChontrol is a cell-type-aware probabilistic framework for single-cell RNA sequencing (scRNA-seq) quality control. It models mitochondrial transcript content using a Gaussian mixture distribution to selectively filter compromised cells while retaining viable populations.