Find open-source science resources
A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
Filters
Health
Domain(1)
Language(1)
License(1)
Source
Type
3 of 6,565 resources
Latent-space probabilistic denoising diffusion model for predicting coarse-grained conformational ensembles of intrinsically disordered proteins and regions from sequence, with GPU/CPU inference, trajectory export, and FAISS-based similarity search (67+ stars, LGPL-3.0)
98B-parameter frontier generative model jointly reasoning over protein sequence, structure, and function, trained on 2.78 billion proteins; generated a novel fluorescent protein (esmGFP) with only 58% sequence identity to known GFPs (EvolutionaryScale, 2024)
AI-assisted mutation nomination approach optimizing protein function by integrating structural and evolutionary constraints into protein inverse folding models, compatible with ProteinMPNN, LigandMPNN, ESM-IF1, and SaProt (Chinese Academy of Sciences, 359+ stars)