ESM3
github.com/evolutionaryscale/esm98B-parameter frontier generative model jointly reasoning over protein sequence, structure, and function, trained on 2.78 billion proteins; generated a novel fluorescent protein (esmGFP) with only 58% sequence identity to known GFPs (EvolutionaryScale, 2024)
Sourced from
- Awesome AI for Science — github.com/evolutionaryscale/esm
- GitHub — github.com/evolutionaryscale/esm
Related resources
Protein structure prediction
AlphaFold 3 inference pipeline for unified biomolecular structure prediction of proteins, nucleic acids, small molecules, ions, and post-translational modifications (Google DeepMind, Nature 2024)
Deep learning library for Chemistry based on Tensorflow
Protein structure prediction from ESM models
First fully open-source model achieving AlphaFold3-level accuracy with 1000x faster binding affinity prediction (MIT)