SkewIT

Skew Index Test for detecting mis-assembled bacterial genomes. SkewIT (Skew Index Test) is a tool for analyzing GC Skew in bacterial genomes. GC Skew is a phenomenon observed in many bacterial genomes wherein the two strands of the chromosome contain different proportions of guanine/cytosine nucleotides. SkewIT quantifies GC Skew using a single metric that can then be compared/analyzed across thousands of bacterial genomes.