Sage (J. Proteome Res. 2023)
github.com/lazear/sageHigh-performance open-source proteomics database search engine written in Rust, converting raw mass spectra into peptide identifications via fragment-indexed searching with machine-learned PSM rescoring (LDA), retention-time prediction, chimeric/co-fragmenting spectrum search, and TMT/label-free quantification at scale; cloud-native with S3/GCS/Azure streaming, Percolator/Mokapot-compatible output, and integration into quantms and OpenMS pipelines, widely adopted in AI-driven proteomics workflows (312+ stars, MIT License, actively maintained)
Sourced from
- Awesome AI for Science — github.com/lazear/sage
- GitHub — github.com/lazear/sage
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