Rectangle
github.com/computationalbiomedicinegroup/rectangleDocumentation Rectangle is an open-source Python package for single-cell-informed cell-type deconvolution of bulk and spatial transcriptomic data. Rectangle presents a novel approach to second-generation deconvolution, characterized by hierarchical signature building for fine-grained cell-type deconvolution, estimation and correction of unknown cellular content, and efficient handling of large-scale single-cell data during signature matrix computation. Rectangle was developed to overcome the current challenges in cell-type deconvolution, providing a robust and accurate methodology while ensuring a low computational profile.
Sourced from
- GitHub — github.com/computationalbiomedicinegroup/rectangle
- bio.tools — rectangle
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