ODesign (OTeam-AI4S, 2025)
github.com/oteam-ai4s/odesignAll-atom generative world model for all-to-all biomolecular interaction design, enabling cross-modality generation of proteins, nucleic acids, small molecules, and cyclic peptides with fine-grained epitope-level control and 2-4 orders of magnitude faster design throughput than modality-specific baselines (316+ stars, Apache 2.0)
Sourced from
- GitHub — github.com/oteam-ai4s/odesign
- Awesome AI for Science — github.com/oteam-ai4s/odesign
Related resources
Protein structure prediction
AlphaFold 3 inference pipeline for unified biomolecular structure prediction of proteins, nucleic acids, small molecules, ions, and post-translational modifications (Google DeepMind, Nature 2024)
Deep learning library for Chemistry based on Tensorflow
Protein structure prediction from ESM models
First fully open-source model achieving AlphaFold3-level accuracy with 1000x faster binding affinity prediction (MIT)