MetaRNN

MetaRNN and MetaRNN-indel are pathogenicity prediction scores for human nonsynonymous SNVs (nsSNVs) and non-frameshift (NF) indels. They integrated information from 28 high-level annotation scores (16 functional prediction scores) and produce an ensemble prediction model with a deep recurrent neural network (RNN). The final prediction is the likelihood of a nsSNV or NF indel being pathogenic.