InstaNovo (InstaDeep, Nature Machine Intelligence 2025)
github.com/instadeepai/instanovoTransformer that translates fragment ion peaks into peptide sequences for database-free de novo sequencing in large-scale proteomics, with InstaNovo+ extending it as a multinomial diffusion model that iteratively refines predicted sequences, plus InstaNovo-P for phosphoproteomics and Winnow for calibrated confidence with FDR control (130+ stars, Apache 2.0, actively maintained)
Sourced from
- Awesome AI for Science — github.com/instadeepai/instanovo
- GitHub — github.com/instadeepai/instanovo
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