Dante

DANTE (Da Amazing NucleoTide Exposer) is an algorithm for genotyping STR (short tandem repeat) alleles from NGS reads. It accounts for natural deviations from the expected sequence including repeat count variation, sequencing errors, ambiguous bases, and complex multi-motif loci. Provides evidence for expanded alleles too long to be captured by a single NGS read, as well as allelic point mutations, small insertions and deletions relevant for diagnostic evaluation. Includes both command-line and graphical user interface.