Clair3 (Nature Computational Science 2022)
github.com/hku-bal/clair3Deep-learning germline small-variant caller for long-read sequencing (PacBio HiFi/ONT) combining fast pileup calling with haplotype-resolved full-alignment calling; widely adopted as a standard in the Human Pangenome Reference Consortium production pipelines and PrecisionFDA truth challenges, with pre-trained models for multiple sequencing platforms, bioconda/Docker distribution, and a companion Clair-skills agent plugin for Claude Code/Codex (HKU-BAL, 394+ stars, BSD-3-Clause, actively maintained)
Sourced from
- Awesome AI for Science — github.com/hku-bal/clair3
- GitHub — github.com/hku-bal/clair3
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