Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

881 of 7,064 resources

Showing 201–250

This model is a fine-tuned version of LiquidAI/LFM2.5-230M optimized for medical chat and consultation.

Active452 months ago

In pursuit of the universal functional for density functional theory (DFT), the OneDFT team from Microsoft Research AI for Science has developed the Skala-1.1 exchange-correlation functional, as introduced in Accurate and scalable exchange-correlation with deep learning, Luise et al. 2025.

Active80.5K2 months ago

CliniGuard Laboratory NER is a transformer-based clinical Named Entity Recognition model developed by Genzeon Platforms for automated extraction of laboratory test results, values, units, reference ranges, and abnormality flags from unstructured clinical text.

Active02 months ago
Python

CliniGuard Diagnosis ICD NER is a transformer-based clinical Named Entity Recognition model developed by Genzeon Platforms for automated extraction of diagnoses, conditions, and support for ICD-10/SNOMED code mapping from unstructured clinical text.

Active172 months ago
Python

CliniGuard Medication NER is a transformer-based clinical Named Entity Recognition model developed by Genzeon Platforms for automated extraction of medication names, dosages, routes, frequencies, and administration details from unstructured clinical text.

Active172 months ago
Python

CliniGuard Clinical Findings NER is a transformer-based clinical Named Entity Recognition model developed by Genzeon Platforms for automated extraction of clinical findings, diseases, conditions, anatomical locations, and clinical modifiers from unstructured clinical text.

Active02 months ago
Python

# DrugGen 2: A disease-aware language model for enhancing drug discovery DrugGen-2 is a disease‑aware language model specialized for generating drug-like SMILES structures based on both disease pathways and protein sequence.

Active462 months ago
Python

Strict automatic scores on the unchanged 1,309-example primary holdout; compare values within each task panel.

Active812 months ago
Python

This is an ONNX version of OpenMed/OpenMed-NER-PharmaDetect-SuperClinical-434M. It was automatically converted and uploaded using this Hugging Face Space.

Active212 months ago

NucleusDiff

Active02 months ago
Active472 months ago

RetroAgent is a 4B-parameter LLM agent for multi-step retrosynthesis planning. It decomposes a target molecule into commercially available building blocks by searching over an AND-OR graph of molecules and reactions, driven entirely by tool calls.

Active412 months ago
Python

TxGravity-30B-A5B is a therapeutics-focused language model fine-tuned from the Gravity-30B-A5B-base. It is trained to predict a broad range of therapeutic properties — small-molecule ADMET, toxicity, drug–target interaction, protein–protein and peptide–MHC interaction, and more — following the…

Active992 months ago
Python

!chronos_logo1

Active5362 months ago
Python

CASCADE: context-aware single-cell modelling links cellular programmes to patient-level disease phenotypes

Active42 months ago

ESMFold2 is a state-of-the-art model for protein structure prediction and design that defines a new frontier for speed and accuracy. The model predicts high-resolution, all-atom 3D protein structures directly from amino acid sequences, with optional multiple sequence alignment (MSA) input for…

Active112 months ago
Python
Active673 months ago
Active2383 months ago
Active2.1K3 months ago

This repository contains a 4-bit GPTQ quantized version of google/medgemma-27b-text-it, optimized for high-throughput inference using vLLM and the Marlin kernel.

Active3463 months ago

# DrugGen 2: A disease-aware language model for enhancing drug discovery DrugGen-2 is a disease‑aware language model specialized for generating drug-like SMILES structures based on both disease pathways and protein sequence.

Active6803 months ago
Python

CENO-P-1B is the multi-species alignment (MSA) post-trained variant of the 1B CENO DNA foundation model, for variant effect prediction (VEP). It carries intraencodingpattern in its config and ships the MSA scoring path (modelingcenop.py), which consumes a per-token seq_idx to score packed MSA…

Active4563 months ago
Python

CENO-1B-131k is the long-context (131k) checkpoint of the 1B CENO DNA foundation model — a causal language model over genomic sequence built on a Nemotron-H Mamba / Attention / Mixture-of-Experts hybrid backbone (no MSA inputs).

Active4523 months ago
Python

CENO-80M-1m is the long-context (1M) checkpoint of the 80M CENO DNA foundation model — a causal language model over genomic sequence built on a Nemotron-H Mamba / Attention / Mixture-of-Experts hybrid backbone (no MSA inputs).

Active3943 months ago
Python

MagNET is a family of neural networks for predicting NMR chemical shifts. This repository contains all models, datasets, and code to reproduce the data in the MagNET paper.

Active03 months ago

!image

Active4233 months ago
Python

A 1.7B-parameter causal language model distilled from Qwen3-30B-A3B on 6,122 STEM chain-of-thought samples using discrepancy-informed knowledge distillation. The training objective emphasizes proof structure, detects reasoning pivot tokens through token-level divergence dynamics, smooths…

Active1.4K3 months ago
Python

Fine-tuned ESM-2 650M with LoRA for predicting protein subcellular localization (10 classes).

Active183 months ago
Python

PhenoVisionL is a Vision Transformer (ViT-Large) model fine-tuned to detect leaf phenological states in plant photographs: green leaves, colored (senescent) leaves, and breaking leaf buds. It was trained on 165,988 iNaturalist records of deciduous woody plants using a two-stage semi-supervised…

Active393 months ago
Python

PhenoVision is a Vision Transformer (ViT-Large) model fine-tuned to detect flowers and fruits in plant photographs. It was trained on 1.5 million human-annotated iNaturalist images and has been used to generate over 30 million new phenology records across 119,000+ plant species, vastly expanding…

Active453 months ago
Python

> NEXUS domain specialist for medical Q&A and clinical reasoning — lightweight & uncensored.

Active16.4K3 months ago
Active73 months ago

> NEXUS domain specialist for medical Q&A and clinical reasoning — lightweight & uncensored.

Active1.6K3 months ago
Python
Active03 months ago
Python
Active7083 months ago
Python
Active433 months ago
Python

Distilling Boltz: Flow Maps for Fast All-Atom Cofolding

Active03 months ago

!Screenshot 2026-07-05 at 2.33.47 AM

Active1.1K3 months ago
Python

### Model Overview TabPFN-3 is a transformer-based foundation model that uses in-context-learning to solve tabular prediction problems in a forward pass. Inference code can be found at https://github.com/PriorLabs/TabPFN. More details can be found in the Model Report.

Active20.6K3 months ago

This repository contains LoRA finetunes of DiffusionGemma (image-conditioned discrete-diffusion LLM) for radiology visual question answering, each paired with an autoregressive Gemma-4 finetune as a controlled baseline. It corresponds to the paper Discrete Diffusion Language Models for Interactive…

Active03 months ago
Python

Fine-tuned gSelformer-MV-Dyn model for predicting dynamic surface tension (DST) curves from SMILES, temperature, and concentration.

Active153 months ago

A native MLX port of OpenMed/privacy-filter-multilingual-v2 for Apple Silicon PII detection and de-identification with OpenMed. This is the unquantized BF16 reference artifact. For the 8-bit sibling, see OpenMed/privacy-filter-multilingual-v2-mlx-8bit.

Active753 months ago

A native MLX port of OpenMed/privacy-filter-multilingual-v2, affine-quantized to 8-bit for faster and smaller Apple Silicon PII detection with OpenMed. For the unquantized BF16 reference, see OpenMed/privacy-filter-multilingual-v2-mlx.

Active363 months ago
Active03 months ago

!ESMC ProtHash Banner

Active463 months ago

!Python

Active03 months ago

🤗 Blog | 📄 Paper | 💻 Code | 🌐 FineMed | 🩺 DoctoBERT

Active203 months ago

🤗 Blog | 📄 Paper | 💻 Code | 🌐 FineMed | 🩺 DoctoBERT

Active4603 months ago
Python