Find open-source science resources
A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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677 of 6,573 resources
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King3Djbl/nexus-medical-GGUF
by King3Djbl> NEXUS domain specialist for medical Q&A and clinical reasoning — lightweight & uncensored.
fableforge-ai/NEXUS-Medical
by fableforge-ai> NEXUS domain specialist for medical Q&A and clinical reasoning — lightweight & uncensored.
Clinical-Reasoning-Hub/pentabrid-27b
by Clinical-Reasoning-Hublowdown-labs/fela-genomics
by lowdown-labslowdown-labs/fela-chemistry
by lowdown-labsgenesisml/decaf
by genesismlDistilling Boltz: Flow Maps for Fast All-Atom Cofolding
!Screenshot 2026-07-05 at 2.33.47 AM
Prior-Labs/tabpfn_3
by Prior-Labs### Model Overview TabPFN-3 is a transformer-based foundation model that uses in-context-learning to solve tabular prediction problems in a forward pass. Inference code can be found at https://github.com/PriorLabs/TabPFN. More details can be found in the Model Report.
This repository contains LoRA finetunes of DiffusionGemma (image-conditioned discrete-diffusion LLM) for radiology visual question answering, each paired with an autoregressive Gemma-4 finetune as a controlled baseline. It corresponds to the paper Discrete Diffusion Language Models for Interactive…
zxcghoul3228/gselformer-mv-dynsurf
by zxcghoul3228Fine-tuned gSelformer-MV-Dyn model for predicting dynamic surface tension (DST) curves from SMILES, temperature, and concentration.
A native MLX port of OpenMed/privacy-filter-multilingual-v2 for Apple Silicon PII detection and de-identification with OpenMed. This is the unquantized BF16 reference artifact. For the 8-bit sibling, see OpenMed/privacy-filter-multilingual-v2-mlx-8bit.
A native MLX port of OpenMed/privacy-filter-multilingual-v2, affine-quantized to 8-bit for faster and smaller Apple Silicon PII detection with OpenMed. For the unquantized BF16 reference, see OpenMed/privacy-filter-multilingual-v2-mlx.
DaisyChainAI/daisychain-genomics
by DaisyChainAI🤗 Blog | 📄 Paper | 💻 Code | 🌐 FineMed | 🩺 DoctoBERT
doctolib-lab/doctobert-fr-base
by doctolib-lab🤗 Blog | 📄 Paper | 💻 Code | 🌐 FineMed | 🩺 DoctoBERT
ratschlab/DeepSpotM
by ratschlabPippinlitli/evolva-qwen-0.5b-heretic
by PippinlitliHeretic-abliterated version of Qwen/Qwen2.5-0.5B-Instruct for the Evolva drug discovery pipeline.
HantaBERT/HantaBERT
by HantaBERTHantaBERT fine-tunes DNABERT-2 on hantavirus RNA sequences for three simultaneous classification tasks: species/lineage, host, and geographic origin. A single forward pass produces predictions for all three tasks along with a 768-dimensional embedding suitable for phylogenetic visualization.
mradermacher/CellHermes-v1.0-GGUF
by mradermacherFor a convenient overview and download list, visit our model page for this model.
zsyjsld/Xinghe1-9B
by zsyjsldXinghe1-9B (杏核) is a specialized large language model fine-tuned for the formalization, computational derivation, and clinical reasoning of Huangdi Neijing. It is based on the Qwen3.5-9B-Instruct architecture and trained using the V3 Double-Purity SFT dataset.
darlednik/LDARNet-2M
by darlednikPretrained LDARNet (~2M params) with learnable DNA tokenization (dynamic chunking + BiMamba-2).
darlednik/LDARNet-110M
by darlednikPretrained LDARNet (~110M params) with learnable DNA tokenization (dynamic chunking + BiMamba-2).
EthanGao123/CellHermes-v1.0
by EthanGao123# Overview This is the CellHermes model, based on the LLaMA-3.1-8B-instruct architecture developed by Meta, fine-tuned using single-cell RNA sequencing (scRNA-seq) datasets from CellxGene and PPI network from BioGRID. CellHermes is an innovative framework for adapting existing large language models…
SeongryongJung/Qwen3-4B-Chemistry-SDPO
by SeongryongJungThis repository contains Chemistry fine-tuned Qwen3-4B checkpoints from the local SciKnowEval-style generalization setup.
PlantGeneAnn is a plant genome foundation model that enables the prediction of various plant genomic elements at single-nucleotide resolution. The model is built upon the PlantBiMoE architecture with a 1D U-Net segmentation head, specifically designed for automated plant genome annotation.
deep-plasma-phenotyping/somascan-ad-classification-tabpfn-v2
by deep-plasma-phenotyping33 lightweight, standalone models that predict discrete Alzheimer's-disease–related phenotypes (e.g. medication use, APOE genotype, vascular pathology, sex) from SomaScan plasma proteomics. The full list is in phenotypes.tsv.
deep-plasma-phenotyping/somascan-ad-regression-tabpfn-v2
by deep-plasma-phenotyping69 lightweight, standalone models that predict continuous Alzheimer's-disease–related phenotypes (cognition, neuropathology burden, motor/functional measures, demographics, a genetic risk score, and longitudinal change) from SomaScan plasma proteomics.
This repository contains a drop-in, Hugging Face–compatible checkpoint converted from https://huggingface.co/microsoft/llava-med-v1.5-mistral-7b. You can load it with the exact same code you use for the original model—no extra conversion steps required.
👋 Join our LiGHT community. 📖 Check out the MeditronFO blog and MeditronFO preprint. 🔜 If you are a clinician join the MOOVE initiative here.
FrenchCastle/sexology-v4
by FrenchCastleSexo-FR is a French-language conversational language model that provides reliable, caring, and evidence-based sexual health information (information en santé sexuelle). It is part of a French public-health initiative whose goal is to make trustworthy sexual-health information more accessible to the…
👋 Join our LiGHT community. 📖 Check out the MeditronFO blog and MeditronFO preprint. 🔜 If you are a clinician join the MOOVE initiative here.
inflammatory-aging-clock/somascan-85
by inflammatory-aging-clockA lightweight plasma-protein aging clock that predicts chronological age from 85 unique inflammatory proteins measured by SomaScan (125 aptamers / SomaScan features). The model is a TabM† student distilled from a TabPFN v2 teacher, so it runs at inference without any TabPFN dependency (small,…
inflammatory-aging-clock/olink-inflammation-92
by inflammatory-aging-clockA lightweight plasma-protein aging clock that predicts chronological age from 92 Olink Inflammation-panel proteins. The model is a TabM† student distilled from a TabPFN v2 teacher, so it runs at inference without any TabPFN dependency (small, DUA-friendly artifacts).
EPFLiGHT/Meditron3-8B
by EPFLiGHTraidium/Jolia
by raidiumJolia is a 3D CT foundation model that encodes images into vector representations program. It encodes a whole 3D CT volume into:
fairydance/molexar-10m-base
by fairydanceMolexar-10M Base is the unconditional base model for Molexar, a unified multimodal molecular foundation model for drug design. It is trained as an autoregressive molecular language model over Fragment-SELFIES, a BRICS-fragment molecular language with validity-preserving decoding and…
fairydance/molexar-10m-omni
by fairydanceMolexar-10M Omni is the universal multi-condition model for Molexar, a unified multimodal molecular foundation model for drug design. It starts from fairydance/molexar-10m-base and is supervised fine-tuned to generate Fragment-SELFIES molecules under scalar molecular-property,…
lotfollahi-lab/TERRA-112M
by lotfollahi-labJEPA-based spatial-transcriptomics foundation model (TERRA). Code & docs: https://github.com/Lotfollahi-lab/terra
iti-visual-analytics/GRamma-12B
by iti-visual-analyticsGRamma-12B is a 12-billion-parameter instruction-tuned language model specialized for the Greek medical domain. It is built on top of Gemma 3 12B Instruct and adapted through parameter-efficient fine-tuning on a collection of Greek and bilingual medical question-answering data.
Full weight-level fine-tuning of InstaDeepAI/nucleotide-transformer-v2-50m-multi-species for binary DNA sequence classification on two GenomicBenchmarks tasks. All parameters are updated rather than using LoRA or a frozen backbone, with a leakage-free train/validation/test protocol and multi-seed…
nvidia/NV-KERMT-70M-v2
by nvidia> Source code, training scripts, and inference utilities for this model: > github.com/NVIDIA-BioNeMo/KERMT > (v2.0 branch / v2.0.0 release tag)
QLoRA adapter for Llama-3.1-8B-Instruct, fine-tuned on PubMedQA for yes / no / maybe biomedical question answering (run5).
BioMatrix is a multimodal biological foundation model that natively integrates 1D sequences, 3D structures, and natural language for both molecules and proteins within a single decoder-only architecture.
antonknee/anisolv
by antonkneenikitaredy/medictron-7B
by nikitaredyA domain-adapted clinical LLM fine-tuned on synthetic Indian medical Q&A records using QLoRA (4-bit quantization) with Unsloth 2x speedup. Built to power the conversational AI layer.
PengJiaMa123/RAMER
by PengJiaMa123This Hugging Face repository stores the official resources for RAMER (reaction-aware multimodal enzyme function representation model).
ProtGPT3-MSA is a multiple-sequence, homolog-conditioned autoregressive protein language model. It is part of the ProtGPT3 family, an open-source suite of promptable and aligned protein language models for protein sequence generation.