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Deep Graph Library for scalable deep learning on graphs, powering molecular modeling, materials discovery, protein interaction networks, and scientific knowledge graph learning across PyTorch, TensorFlow, and MXNet backends (14K+ stars)

Scientific equation discovery and symbolic regression using LLMs, combining code generation with evolutionary search (ICLR 2025 Oral)

AI agent for therapeutic reasoning across a universe of tools, achieving 92.1% accuracy in drug reasoning and outperforming GPT-4o by 25.8% (Harvard MIMS, 2025)

Family of diffusion protein language models demonstrating versatile generative and predictive capabilities for protein sequences and structures, including multimodal co-generation, conditional folding, inverse folding, motif scaffolding, and representation learning, with open pretrained weights and training scripts (327+ stars, ICML 2024, ICLR 2025, ICML 2025 Spotlight)

Large-scale flow-based protein backbone generator utilizing hierarchical fold class labels for conditioning with a tailored scalable transformer architecture, enabling controllable de novo protein design (264+ stars)

Public release of Profluent's ProGen3 protein language model family, including PMC-15B supporting sequence- and structure-conditioned generation for protein design, zero-shot fitness prediction, and antibody engineering with state-of-the-art performance on fitness and docking benchmarks (114+ stars, Apache 2.0)

Highly focused on medical Training datasets ; + Upgraded inplace

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This model classifies facial skin images into 6 common dermatological conditions using a fine-tuned EfficientNetV2B0 architecture.

darkknight25/deepseek-16b-medical-GPT is a fine-tuned version of deepseek-ai/deepseek-l6b-moe-chat, optimized for medical question answering, reasoning, and clinical summarization using QLoRA and open-access healthcare datasets.

Unsloth Dynamic 2.0 achieves superior accuracy & outperforms other leading quants.

This is a merge of pre-trained language models created using mergekit, combining the specialty and general reasoning skills of Esper 3 8b and Shining Valiant 3 8b.

A library for estimating thermochemical properties of molecules and adsorbates using group additivity.

Segment Anything in 3D medical images and videos, extending SAM2 to volumetric and temporal medical imaging with state-of-the-art zero-shot segmentation performance across CT, MRI, and surgical video (arXiv 2025)

For a convenient overview and download list, visit our model page for this model.

For a convenient overview and download list, visit our model page for this model.

For a convenient overview and download list, visit our model page for this model.

For a convenient overview and download list, visit our model page for this model.

Unsloth Dynamic 2.0 achieves superior accuracy & outperforms other leading quants.

RaDialog

AI agent for biological discovery and research automation

!image # Compumacy-Experimental_MF ## A Specialized Language Model for Clinical Psychology & Psychiatry

Welcome to IBM's series of large foundation models for sustainable materials. Our models span a variety of representations and modalities, including SMILES, SELFIES, 3D atom positions, 3D density grids, molecular graphs, and other formats.

This is the official pre-trained model introduced in DNABERT-2: Efficient Foundation Model and Benchmark For Multi-Species Genome .

An ontology of qualifications, distinctions, and certifications that uses the Phenotype And Trait Ontology term quality (PATO:0000001) as a root term.

Original code at (https://github.com/Edoar-do/HuBERT-ECG)

> [!IMPORTANT] > 🎉 Check out the latest version of Phikon here: Phikon-v2 > > Phikon is a self-supervised learning model for histopathology trained with iBOT.

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Model documentation: MedGemma

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

In silico directed evolution framework using few-shot active learning to optimize protein activities, enabling rapid protein engineering with minimal experimental data (352+ stars, 2023)

Extensible chemistry toolkit for MCP-enabled AI assistants, exposing molecule analysis, property prediction, and reaction synthesis tools through unified Python/MCP interfaces for chemistry agents and research workflows (Apache 2.0, 2025)

This model mlx-community/medgemma-27b-text-it-bf16 was converted to MLX format from google/medgemma-27b-text-it using mlx-lm version 0.25.1.

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Large language-and-vision assistant for biomedicine, instruction-tuned on GPT-4-generated biomedical multimodal instruction-following data to enable conversational visual question answering over radiology, pathology, and microscopy images, establishing open recipes for adapting general vision-language models to the biomedical domain (Microsoft Research & University of Washington, 2.2K+ stars)

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

FloraSense is a fine-tuned Vision Transformer (ViT) model designed for accurate classification of plant species and flora-related imagery. It builds on top of the powerful google/vit-base-patch16-224 base model and is fine-tuned on the PlanterGARDENEDITION dataset curated by Sisigoks, which…

FineMedLM-o1

Multimodal LLM for scientific charts and diagrams understanding/generation