Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

1,027 of 6,573 resources

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Idle271 year ago
Python

Vision-language pathology foundation model using contrastive learning on histopathology image-text pairs, enabling zero-shot classification, slide-level retrieval, and multimodal reasoning across diverse cancer types (Mahmood Lab, 494+ stars)

Idle5211 year ago
Python
NOASSERTION

This deep learning model is designed for ECG image classification, fine-tuned using ResNet-50. It can classify ECG images into different categories to assist in heart disease detection.

Idle41 year ago
Python

Python wrapper for [bedtools](https://github.com/arq5x/bedtools).

Idle3301 year ago
Python
NOASSERTION

Diabetica: Adapting Large Language Model to Enhance Multiple Medical Tasks in Diabetes Care and Management

Idle711 year ago
Python

PPTStab: Prediction and Designing of thermostable proteins with a desired melting temperature

Idle01 year ago
Python

INDUS-Retriever-small (previously nasa-smd-ibm-st.38m) is a Bi-encoder sentence transformer model, that is fine-tuned from distilled version of nasa-smd-ibm-v0.1 encoder model. it is a smaller version of nasa-smd-ibm-st with better performance, using fewer parameters (shown below).

Idle111 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle6851 year ago
Python

Neural optical understanding for academic documents, transforms scientific PDFs to Markdown with mathematical formula support

Idle10.1K1 year ago
Python
MIT

Generate comprehensive reviews from arXiv papers and convert to blog posts

Idle8441 year ago
Python
Apache-2.0

Microsoft's AI-powered ab initio biomolecular dynamics simulation achieving quantum-mechanical accuracy for proteins with 10,000+ atoms, orders of magnitude faster than DFT using protein fragmentation and ML force fields (Nature 2024)

Idle5761 year ago
Python
MIT

Equivariant graph attention Transformer (ICLR2023)

Idle2881 year ago
Python
MIT

Extension of ProteinMPNN for protein sequence design in the context of small-molecule ligands, metal ions, and nucleic acids, enabling binding site engineering and co-factor redesign (Baker Lab)

Idle6111 year ago
Python
MIT

Physics-AI hybrid modeling for fine-grained weather forecasting (NeurIPS'24)

Idle1721 year ago
Python

Geometric deep learning model predicting transcriptional outcomes of novel single- and multi-gene perturbations using gene–gene knowledge graphs, 40% higher precision than prior methods on combinatorial perturbation prediction (Stanford, Nature Biotechnology 2024)

Idle3901 year ago
Python
MIT

# GPN trained on Arabidopsis thaliana and 7 other Brassicales See https://github.com/songlab-cal/gpn for more details.

Idle5.4K1 year ago
Python

Open-source medical large language model for complex clinical reasoning, extending the o1 long-chain-of-thought paradigm to biomedical question answering and diagnostic inference (FreedomIntelligence, 1.3K+ stars)

Idle1.3K1 year ago
Python

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Idle1.9K1 year ago
Python

The Clinical Assertion and Negation Classification BERT is introduced in the paper Assertion Detection in Clinical Notes: Medical Language Models to the Rescue? . The model helps structure information in clinical patient letters by classifying medical conditions mentioned in the letter into…

Idle1.8K1 year ago
Python

Model from this repo. Model used to be in Dropbox/GDrive, leading to issues with download

Idle141 year ago
Python

# FremyCompany/BioLORD-2023 This model was trained using BioLORD, a new pre-training strategy for producing meaningful representations for clinical sentences and biomedical concepts.

Idle445.3K1 year ago
Python

# FremyCompany/BioLORD-2023-M This model was trained using BioLORD, a new pre-training strategy for producing meaningful representations for clinical sentences and biomedical concepts.

Idle37.1K1 year ago
Python

A module for solving and visualizing the Schrödinger equation.

Idle1.2K1 year ago
Python
BSD-3-Clause

Comprehensive toolkit for high-quality PDF content extraction with layout detection, formula recognition, and OCR

Idle9.9K1 year ago
Python
AGPL-3.0

# MMedS-Llama3 💻Github Repo 🖨️arXiv Paper

Idle9481 year ago
Python

### Welcome to Nidum! At Nidum, we believe in pushing the boundaries of innovation by providing advanced and unrestricted AI models for every application. Dive into our world of possibilities and experience the freedom of Nidum-Llama-3.2-3B-Uncensored, tailored to meet diverse needs with…

Idle4.3K1 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle1.2K1 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle1921 year ago
Python

Single-cell transformer foundation model pretrained on 104M human transcriptomes via masked gene prediction, enabling transfer learning for cell type classification, gene network analysis, and in silico perturbation with limited labeled data (Nature 2023, V2 2024)

Idle01 year ago
Python

We identified and fixed an issue related to a wrong permutation of some projections, which affects generation quality. To use the new model revision, please load as follows:

Idle2.8K1 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle5331 year ago
Python

This model aims to be a base template for new models. It has been generated using this raw template.

Idle1291 year ago
Python

Large-scale biomolecular instruction dataset for chemistry/biology LLMs (ICLR2024)

Idle2941 year ago
Python
MIT

Large Language Models for automated open-domain scientific hypotheses discovery (ACL 2024, ICML Best Poster)

Idle471 year ago
Python

Descriptor computation(chemistry) and (optional) storage for machine learning.

Idle2801 year ago
Python
NOASSERTION

Indus (previously known as nasa-smd-ibm-v0.1) is a RoBERTa-based, Encoder-only transformer model, domain-adapted for NASA Science Mission Directorate (SMD) applications. It's fine-tuned on scientific journals and articles relevant to NASA SMD, aiming to enhance natural language technologies like…

Idle551 year ago
Python

Indus-Retriever (nasa-smd-ibm-st-v2) is a Bi-encoder sentence transformer model, that is fine-tuned from nasa-smd-ibm-v0.1 encoder model. it is an updated version of nasa-smd-ibm-st with better performance (shown below). It's trained with 271 million examples along with a domain-specific dataset of…

Idle27.9K1 year ago
Python

MediFlow se trata de un modelo inicializado con xlnet-large-cased y adaptado con preguntas y especialidades para poder realizar Derivaciones Automatizadas en Servicios Hospitalarios. El dataset se puede encontrar de manera pública y se trata de MedDialog EN.

Idle61 year ago
Python

If you are unsure how to use GGUF files, refer to one of TheBloke's READMEs for more details, including on how to concatenate multi-part files.

Idle3811 year ago
Python

> [!IMPORTANT] > Better using New version of ChemLLM! > AI4Chem/ChemLLM-7B-Chat-1.5-DPO or AI4Chem/ChemLLM-7B-Chat-1.5-SFT

Idle1.1K1 year ago
Python

Chemma-2B is a continually pretrained gemma-2b model for organic molecules. It is pretrained on 40B tokens covering 110M+ molecules from PubChem as well as their chemical properties (molecular weight, synthetic accessibility score, drug-likeness etc.) and similarities (Tanimoto distance between…

Idle471 year ago
Python

## Quick Start ```Python from transformers import AutoTokenizer, AutoModel

Idle381 year ago
Python

Universal chart comprehension and reasoning model

Idle1351 year ago
Python
NOASSERTION

Utility that performs integrated analyses of 'gene' data (a set of genes or other genomic features) with 'peak' data (a set of regions, for example ChIP peaks) to identify the genes nearest to each peak, and vice versa.

Idle51 year ago
Python
Artistic-2.0

Transform arXiv research papers into engaging presentations and YouTube-ready videos

Idle121 year ago
Python

Batteries included genomic analysis pipeline for variant and RNA-Seq analysis, structural variant calling, annotation, and prediction.

Stale1K2 years ago
Python
MIT

Materials informatics benchmark

Stale2142 years ago
Python
MIT

Convert PDF files into editable slides with three lines of code

Stale162 years ago
Python
GPL-3.0

Structure-aware prefix adaptation for integrating LLMs with knowledge graphs (ACM MM 2024)

Stale2112 years ago
Python
MIT

Powerful and flexible machine learning platform for drug discovery, providing comprehensive tools for molecular property prediction, generative models, knowledge graph reasoning, and reaction prediction with PyTorch backend (1.5K+ stars)

Stale1.6K2 years ago
Python
Apache-2.0