Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

1,030 of 6,584 resources

Showing 751800

Idle8K1 year ago
Python
Idle24K1 year ago
Python

This is the official pre-trained model introduced in DNABERT-2: Efficient Foundation Model and Benchmark For Multi-Species Genome .

Idle535.6K1 year ago
Python

An ontology of qualifications, distinctions, and certifications that uses the Phenotype And Trait Ontology term quality (PATO:0000001) as a root term.

Idle11 year ago
Python
MIT

> [!IMPORTANT] > 🎉 Check out the latest version of Phikon here: Phikon-v2 > > Phikon is a self-supervised learning model for histopathology trained with iBOT.

Idle19.8K1 year ago
Python

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Idle291 year ago
Python

Model documentation: MedGemma

Idle141 year ago
Python

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Idle151 year ago
Python

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Idle251 year ago
Python

In silico directed evolution framework using few-shot active learning to optimize protein activities, enabling rapid protein engineering with minimal experimental data (352+ stars, 2023)

Idle3641 year ago
Python
NOASSERTION

Extensible chemistry toolkit for MCP-enabled AI assistants, exposing molecule analysis, property prediction, and reaction synthesis tools through unified Python/MCP interfaces for chemistry agents and research workflows (Apache 2.0, 2025)

Idle691 year ago
Python
Apache-2.0

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Idle271 year ago
Python

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Idle1741 year ago
Python

An Evolutionary-scale Model (ESM) for protein function prediction from amino acid sequences using the Gene Ontology (GO). Based on the ESM2 Transformer architecture, pre-trained on UniRef50, and fine-tuned on the AmiGO dataset, this model predicts the GO subgraph for a particular protein sequence -…

Idle1201 year ago
Python

FloraSense is a fine-tuned Vision Transformer (ViT) model designed for accurate classification of plant species and flora-related imagery. It builds on top of the powerful google/vit-base-patch16-224 base model and is fine-tuned on the PlanterGARDENEDITION dataset curated by Sisigoks, which…

Idle2481 year ago
Python

FineMedLM-o1

Idle151 year ago
Python

Multimodal LLM for scientific charts and diagrams understanding/generation

Idle2.4K1 year ago
Python
Apache-2.0

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Idle37.5K1 year ago
Python

Universal 3D molecular pretraining framework with 209M conformations, scaling to 1.1B parameters (Uni-Mol2) on 800M conformations for molecular property prediction, docking, and quantum chemistry (ICLR 2023, NeurIPS 2024)

Idle1.1K1 year ago
Python
MIT

End-to-end RNA 3D structure prediction using RNA language model pretrained on 23.7M sequences, outperforming existing methods and human expert groups on RNA-Puzzles and CASP15 (Nature Methods 2024)

Idle2431 year ago
Python
Apache-2.0

Advanced paper search agent powered by large language models, autonomously invoking search tools, reading papers, and selecting references to deliver comprehensive and accurate results for complex scholarly queries (1.5K+ stars, Apache 2.0, 2024)

Idle1.6K1 year ago
Python
Apache-2.0

Industrial-grade reinforcement-learning-based generative platform for de novo molecular design with transformer architectures, supporting multi-objective optimization, scaffold decoration, and curriculum learning (AstraZeneca MolecularAI, REINVENT 4, 2024)

Archived3771 year ago
Python
Apache-2.0

Dans-PersonalityEngine-V1.3.0-24b Dans-PersonalityEngine-V1.3.0-24b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀…

Idle2.9K1 year ago
Python

Dans-PersonalityEngine-V1.3.0-12b Dans-PersonalityEngine-V1.3.0-12b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀…

Idle891 year ago
Python

Dans-PersonalityEngine-V1.1.0-12b This model series is intended to be multifarious in its capabilities and should be quite capable at both co-writing and roleplay as well as find itself quite at home performing sentiment analysis or summarization as part of a pipeline.

Idle241 year ago
Python

Dans-PersonalityEngine-V1.2.0-24b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀ ⠀⢌⠀⠤⠀⢠⣞⣾⡗⠁⠀⠈⠁⢨⡼⠀⠀⠀⢀⠀⣀⡤⣄⠄⠈⢻⡇⠀⠐⣠⠜⠑⠁⠀⣀⡔⡿⠨⡄…

Idle761 year ago
Python

# fernandoruiz/medgemma-4b-it-Q4_0-GGUF This model was converted to GGUF format from google/medgemma-4b-it using llama.cpp via the ggml.ai's GGUF-my-repo space. Refer to the original model card for more details on the model.

Idle371 year ago
Python

General purpose tools for high-throughput catalysis.

Idle1041 year ago
Python
GPL-3.0

Unsloth Dynamic 2.0 achieves superior accuracy & outperforms other leading quants.

Idle5.7K1 year ago
Python

Unsloth Dynamic 2.0 achieves superior accuracy & outperforms other leading quants.

Idle1.2K1 year ago
Python

# Mol-Llama-3.1-8B-Instruct [Project Page] [Paper] [GitHub]

Idle1491 year ago
Python

Self-Referencing Embedded Strings (SELFIES): A 100% robust molecular string representation.

Idle8571 year ago
Python
Apache-2.0

An open, community-driven registry of conference and event venues. EVR assigns persistent identifiers (PIDs) to make referencing venues FAIR. This is similar to how ORCID assigns PIDs to researchers and ROR assigns PIDs to research organizations. This benefits researchers assembling information about in-person conferences and events by enabling them to refer in an unambiguous way to the venue where it takes place. This repository follows the [Open Data, Open Code, Open Infrastructure (O3) principles](https://www.nature.com/articles/s41597-024-03406-w), meaning that the data and code are all in one repository that anyone can contribute to.

Idle01 year ago
Python
MIT

ValidSense is a toolbox for assessing agreement between two quantitative methods or devices measuring the same quantity using the Limits of Agreement (LoA) analysis, also known as the Bland-Altman analysis.

Idle21 year ago
Python
MIT

Automated hypothesis testing with agentic sequential falsifications

Idle2801 year ago
Python

Bioinspired multi-agent intelligent graph reasoning system that autonomously traverses ontological knowledge graphs to generate, critique, and refine novel research hypotheses, demonstrated on bio-inspired materials discovery with cross-disciplinary connection mining (MIT Lamm Group, 2024)

Idle6301 year ago
Python
Apache-2.0

Systematic medical RAG toolkit for question answering over PubMed, StatPearls, textbooks, and Wikipedia, supporting multiple retrievers, domain LLMs, and follow-up-query workflows for benchmarked clinical/biomedical QA (ACL Findings 2024)

Idle5801 year ago
Python
NOASSERTION

🚀 Meerkat-8B is a new instruction-tuned medical AI system of the Meerkat model family. The model was based on the Meta's Llama-3-8B-Instruct model and fine-tuned using our new synthetic dataset consisting of high-quality chain-of-thought reasoning paths sourced from 18 medical textbooks, along…

Idle4261 year ago
Python

🚀 Meerkat-7B-v1.0 is an instruction-tuned medical AI system that surpasses the passing threshold of 60% for the United States Medical Licensing Examination (USMLE) for the first time among all 7B-parameter models. The model was trained using our new synthetic dataset consisting of high-quality…

Idle921 year ago
Python

AI-powered tool that automatically converts academic papers (PDF) into presentation slides

Idle151 year ago
Python

Diffusion-based molecular docking achieving SOTA blind docking performance, treating ligand pose prediction as generative diffusion over SE(3), with DiffDock-L update for improved generalization (MIT CSAIL, ICLR 2023)

Idle1.6K1 year ago
Python
MIT

This is https://huggingface.co/kingabzpro/Qwen-3-32B-Medical-Reasoning applied to https://huggingface.co/Qwen/Qwen3-32B Original model card created by @kingabzpro

Idle3421 year ago
Python

GP-MoLFormer is a class of models pretrained on SMILES string representations of 0.65-1.1B molecules from ZINC and PubChem. This repository is for the model pretrained on all the unique molecules from both datasets.

Idle1.5K1 year ago
Python

Unified benchmarking framework for protein representation learning, providing standardized interfaces for pre-training and diverse downstream tasks including structure prediction, fitness prediction, and property prediction across multiple protein datasets and model architectures (ICLR 2024, 273+ stars, MIT License)

Idle2751 year ago
Python
MIT

## Model Description EYE-Llama_gqa is a large language model specifically designed for ophthalmic question-answering (QA). It is built upon the Llama 2 architecture and fine-tuned on a the EYE-lit and EYE-QA+ dataset.

Idle1651 year ago
Python

This model card describes the ClinicalBERT model, which was trained on a large multicenter dataset with a large corpus of 1.2B words of diverse diseases we constructed. We then utilized a large-scale corpus of EHRs from over 3 million patient records to fine tune the base language model.

Idle21.2K1 year ago
Python

Efficient foundation models for PDEs with pretrained transformer-based neural operators and downstream task fine-tuning pipelines, HuggingFace integration for models and datasets (ETH Zurich CAMLab, arXiv 2024)

Idle1941 year ago
Python

This project fine-tunes the meta-llama/Llama-4-Scout-17B-16E-Instruct model using a medical reasoning dataset (FreedomIntelligence/medical-o1-reasoning-SFT) with 4-bit quantization for memory-efficient training.

Idle01 year ago
Python

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Idle2771 year ago
Python