Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

7 of 7,083 resources

PanAbyss is a tool for exploring and visualizing pangenome graphs. It allows users to search for and display regions of a pangenome using coordinates on a reference individual or based on annotations. It also enables searching for regions associated with a selected set of individuals (for example, those linked to a phenotype), computing proximity trees, and retrieving sequences from a given region.

Active32 weeks ago
Python
NOASSERTION

dadi is a bioinformatics tool for inferring demographic history and selection from genetic data using diffusion approximations, offering speed and flexibility in modeling population dynamics. It supports up to three populations with customizable parameters and provides efficient computational performance.

Active83 weeks ago
Python
NOASSERTION

RejuvenationKit is an open-source Python toolkit for reproducible auditing and analysis of longitudinal preclinical rejuvenation studies. It provides protocol-aware missingness checks, experimental-confounding diagnostics, attrition and analysis-readiness profiling, covariance-aware multichannel change detection, sequential response monitoring, randomized longitudinal inference, visualization, and integrity-tracked report bundles.

Active01 month ago
Python
NOASSERTION

A Python script that converts positional information from a SAM dataset into interval format with 0-based start and 1-based end. CIGAR string of SAM format is used to compute the end coordinate.

Active372 months ago
Python
NOASSERTION

A two-step desktop GUI application for RNA-seq differential gene expression (DEG) analysis. Step 1 reads raw GDC/TCGA STAR gene-count files together with a GDC sample sheet, matches samples to a Tumor/Normal design, and runs PyDESeq2 to produce normalized counts and DEG statistics. Step 2 generates publication-style volcano plots, MA plots, summary bar charts, and expression heatmaps (with optional gene labeling) from the results, exportable as PNG, PDF, SVG, or TIFF. Requires no coding from the user.

Active02 months ago
Python
NOASSERTION

RFdiffusion is an open source method for structure generation, with or without conditional information (a motif, target etc).

Active3K2 months ago
Python
NOASSERTION

Circlator is a tool to circularize genome assemblies. It will attempt to identify each circular sequence and output a linearised version of it. It does this by assembling all reads that map to contig ends and comparing the resulting contigs with the input assembly.

Stale2592 years ago
Python
NOASSERTION