Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

8 of 6,590 resources

Automated pipeline for proteome-scale protein-protein interaction screening with AlphaFold-Multimer and AlphaFold 3, supporting flexible inputs (UniProt IDs, FASTA, residue regions, multimers, AF3 JSON features) and integrated downstream analysis for hit prioritization (Kosinski Lab, EMBL, Nature Protocols 2024, 317+ stars, GPL-3.0)

Active3201 week ago
Python
GPL-3.0

Unified Python framework for bulk, single-cell, and spatial RNA-seq multi-omics analysis with deep learning deconvolution (VAE) and graph neural networks, bridging Bindea, Bindea, scanpy and squidpy ecosystems (Nature Communications 2024)

Active1.2K2 weeks ago
Python
GPL-3.0

AI coding assistant for JupyterLab with agent mode, supporting arbitrary LLM providers (2025+)

Active3254 weeks ago
Python
GPL-3.0

Neural network-based cryo-EM heterogeneous reconstruction, modeling continuous 3D structure distributions from single-particle images, with CryoDRGN-ET extending to in-cell cryo-electron tomography (MIT CSAIL, Nature Methods 2021/2024)

Active3831 month ago
Python
GPL-3.0

Self-hostable scientific claim-verification and literature-review tool combining Semantic Scholar retrieval, bibliometric scoring, and LLM-based evidence synthesis for large-batch validation workflows

Active121 month ago
Python
GPL-3.0

Fast spike sorting with drift correction for extracellular electrophysiology, enabling universal neural spike sorting via deep learning on high-density neural probe recordings (MouseLand, 609+ stars)

Active6234 months ago
Python
GPL-3.0

Convert PDF files into editable slides with three lines of code

Stale162 years ago
Python
GPL-3.0

Single-cell BERT for gene expression

Stale3592 years ago
Python
GPL-3.0