Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

27 of 6,223 resources

Active1491 day ago
JavaScript

GO Rules are a way of documenting the set of filters and reports that should apply to GAF annotation data. Some rules are expressed as SPARQL on a triplestore, some are code in the GAF parsing software, ontobio.

Active493 days ago
JavaScript
BSD-3-Clause

Interactive browser for the complete Human Phenotype Ontology (~19,800 terms), with a graph-based term explorer and a clinical profile analyzer for phenotype similarity, differential diagnosis, and gene prioritization.

Active01 week ago
JavaScript
CC-BY-4.0

The Basic Register of Thesauri, Ontologies & Classifications (BARTOC) is a database of Knowledge Organization Systems and KOS related registries. The main goal of BARTOC is to list as many Knowledge Organization Systems as possible at one place in order to achieve greater visibility, highlight their features, make them searchable and comparable, and foster knowledge sharing. BARTOC includes any kind of KOS from any subject area, in any language, any publication format, and any form of accessibility. BARTOC’s search interface is available in 20 European languages and provides two search options: Basic Search by keywords, and Advanced Search by taxonomy terms. A circle of editors has gathered around BARTOC from all across Europe and BARTOC has been approved by the International Society for Knowledge Organization (ISKO).

Active292 weeks ago
JavaScript
MIT

This is the Provenance Information for Materials Science (PRIMA) Ontology, version 3.0, aligned with PMDco v3 and based on BFO (Basic Formal Ontology). This complete module imports all PRIMA modules (core, data-analysis-lifecycle, dataset, experiment, and computational) in their v3.0 versions. [from https://purls.helmholtz-metadaten.de/prima/complete]

Active12 weeks ago
JavaScript
CC-BY-3.0

Aggregate results from bioinformatics analyses across many samples into a single report.

Active1.5K3 weeks ago
JavaScript
GPL-3.0

AI-powered note linking and research graph navigation

Active5.2K3 weeks ago
JavaScript
NOASSERTION

compareMS2 is a tool for comparing sets of (tandem) mass spectra for clustering samples, molecular phylogenetics, identification of biological species or tissues, and quality control. compareMS2 currently consumes Mascot Generic Format, or MGF, and produces output in a variety of common image and distance matrix formats.

Active43 weeks ago
JavaScript
MIT

Web application and service for visualizing small- to medium-scale models of gene regulatory networks. It automatically lays out either an unweighted or weighted network graph based on an Excel input spreadsheet containing an adjacency matrix where regulators are named in the columns and target genes in the rows. It is best-suited for visualizing networks of fewer than 35 nodes and 70 edges and has general applicability.

Active173 weeks ago
JavaScript
BSD-3-Clause

Auto-generates clean, customizable academic CVs from open research data (OpenAlex, ORCID, Crossref, DataCite, Open Editors Plus). A single canonical CV object drives every output format (HTML, PDF, DOCX, LaTeX, Markdown); citations render through CSL; and the account holder is matched by persistent identifier (ORCID / OpenAlex ID) rather than name string. Free for individuals, open-source, and FAIR by design.

Active01 month ago
JavaScript
Apache-2.0

A static web application presents an interactive knowledge graph of single-cell long-read RNA sequencing literature synthesized from seven source papers. Users navigate mind-tree, network graph, guided learning-path, and Sankey views linking platforms, protocols, methods, and software. A benchmark tab provides 34 question-answer pairs with category and difficulty filters, exportable as JSON or CSV for LLM and agent evaluation.

Active01 month ago
JavaScript
MIT

Quantum chemisttry web platform that brings all the necessary tools to perform quantum chemistry in a user-friendly web interface.

Active761 month ago
JavaScript
GPL-3.0

Multi-PDF conversation, retrieval, and citation in Zotero with commercial/local models (Ollama), MCP support

Active2.5K1 month ago
JavaScript
AGPL-3.0

Galaxy Tool Shed repositories maintained and developed by the GalaxyP community

Active361 month ago
JavaScript
MIT

Interactive explorer for single-cell transcriptomics data enabling visualization of UMAP/t-SNE embeddings, differential expression analysis, and cross-dataset comparison through a fast web-based interface; widely adopted for exploring atlas-scale single-cell datasets and integrating with AI/ML analysis workflows (773+ stars, MIT License)

Active7731 month ago
JavaScript
MIT

FlowVision is offline flow cytometry analysis software for Windows and macOS. It supports FCS 2.0, 3.0, 3.1 and 3.2 file formats, polygon/rectangle/ellipse/quadrant gating with auto-fit (snap to cluster), spillover compensation, biexponential and hyperlog scales, MFI statistics (median, geometric mean, CV%), multi-file batch analysis with per-file gate overrides, and hierarchical gating. Spectral unmixing supports linear, NNLS, and Poisson-weighted least squares algorithms, with autofluorescence extraction and spillover spreading matrix. UMAP dimensionality reduction with reproducible seed and landmark mode for high-parameter panels. Imports FlowJo .wsp (compensation matrix) and exports gates to FlowJo .wsp and Gating-ML 2.0 (ISAC open standard) for interoperability with FlowJo, R/flowWorkspace/CytoML, and FCS Express.

Active01 month ago
JavaScript
Proprietary

Modular and universal bioinformatics, Bionode provides pipeable UNIX command line tools and JavaScript APIs for bioinformatics analysis workflows.

Archived3131 month ago
JavaScript
MIT
Active23 months ago
JavaScript

JavaScript genome browser that is highly customizable via plugins and track customizations.

Active4744 months ago
JavaScript
NOASSERTION

Ribocentre is designed to contain comprehensive information of all natural ribozymes.

Active15 months ago
JavaScript

Biofactoid is a web-based system that empowers authors to capture and share machine-readable summaries of molecular-level interactions described in their publications.

Idle291 year ago
JavaScript
MIT

SMILES-Mapper is a small web app that allows students to easily visualize how SMILES & InChI strings are created together with other mol-block file formats such as .mol and .sdf files.

Stale12 years ago
JavaScript
MIT

Open source web framework for small molecule analysis based on Django.

Stale413 years ago
JavaScript
NOASSERTION

JavaScript library that can be used to generate interactive and highly customizable web-based genome browsers.

Stale2814 years ago
JavaScript
Apache-2.0

Embeddable genome viewer. Integration data from a wide variety of sources, and can load data directly from popular genomics file formats including bigWig, BAM, and VCF.

Stale2296 years ago
JavaScript
BSD-2-Clause

JavaScript library for drawing canvas-based gene diagrams.

Stale767 years ago
JavaScript

D3 JavaScript based genome viewer. Constructs SVGs.

Stale3311 years ago
JavaScript
GPL-2.0