Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

7 of 7,083 resources

SPAdes (St. Petersburg genome assembler) is an assembly toolkit containing various assembly pipelines and the de-facto standard for prokaryotic genome assemblies.

Active9631 week ago
C++
NOASSERTION

A collection of object-oriented software tools for problems involving chemical kinetics, thermodynamics, and transport processes.

Active8621 week ago
C++
NOASSERTION

The modern C++ library for sequence analysis.

Active4611 month ago
C++
NOASSERTION

Oxford Nanopore's official deep-learning basecaller for nanopore sequencing, converting raw electrical signals into DNA/RNA sequences with integrated modified-base (methylation) detection and efficient CPU/GPU inference; foundational tool for long-read genomics, epigenetics, and real-time sequencing analysis (nanoporetech, 846+ stars, actively maintained)

Active8661 month ago
C++
NOASSERTION

Structural variant and indel caller for mapped sequencing data.

Archived4671 year ago
C++
NOASSERTION

SKESA is a de-novo sequence read assembler for microbial genomes. It uses conservative heuristics and is designed to create breaks at repeat regions in the genome. This leads to excellent sequence quality without significantly compromising contiguity.

Stale1272 years ago
C++
NOASSERTION

A suite of algorithms for matching position weight matrices (PWM) against DNA sequences. It features advanced matrix matching algorithms implemented in C++ that can be used to scan hundreds of matrices against chromosome-sized sequences in few seconds. MOODS can also process high-order PWMs with dependencies between adjacent positions and sequence variants such as SNPs, insertions and deletions.

Stale1183 years ago
C++
NOASSERTION