Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

40 of 5,893 resources

Technical Report 🧬

Active7.1K1 day ago
Python

gemma4-12b-bioinfo is a fine-tuned Gemma 4 12B instruction model for bioinformatics, genomics, and computational biology question answering.

Active1202 days ago
Python

> VIDRAFT FINAL-Bench — chemistry-specialized 218B MoE, served via the DELPHI 5-Phase inference cascade.

Active281 week ago
Python

HealthJudge is a domain-adapted helpfulness evaluator for health-related Community Notes. It is designed to judge whether a note provides helpful context for a potentially misleading social-media post, following the Community Notes helpfulness criteria.

Active311 week ago
Python

ProtGPT3-MSA is a multiple-sequence, homolog-conditioned autoregressive protein language model. It is part of the ProtGPT3 family, an open-source suite of promptable and aligned protein language models for protein sequence generation.

Active1751 week ago
Python

Target-Conditioned Molecular Ideation Model for Drug Discovery Research

Active02 weeks ago
Python

Genos-m is a foundation model for human-associated microbial genomes. It is trained to model microbial DNA sequences at single-nucleotide resolution and supports ultra-long genomic contexts up to one million tokens.

Active312 weeks ago
Python

Qwen3-8B-syco_med-gated-attention-FT is a plug-and-play gated attention weight released for AI safety research.

Active03 weeks ago
Python

Apertus-8B-MeditronFO is a 8B-parameter medical specialist LLM, produced by supervised fine-tuning of Apertus-8B-Instruct on the Fully Open Meditron Corpus.

Active3813 weeks ago
Python

Apertus-70B-MeditronFO is a 70B-parameter medical specialist LLM, produced by supervised fine-tuning of Apertus-70B-Instruct on the Fully Open Meditron Corpus.

Active3973 weeks ago
Python

Gemma 4 E2B fine-tuned on 225K drug–target pairs for novel small-molecule generation.

Active253 weeks ago
Python

MedPsy-4B is a state-of-the-art, text-only medical and healthcare language model purpose-built for edge deployment. Built on top of Qwen3-4B-Thinking-2507 and post-trained with a multi-stage pipeline (supervised fine-tuning + reinforcement learning) on curated medical data, it surpasses models…

Active1.4K1 month ago
Python

Duchifat-2.3-Instruct is a state-of-the-art, instruction-tuned Large Language Model developed by TopAI. As the flagship of the Duchifat series, this model represents a fundamental breakthrough in how Hebrew is processed, reasoned, and generated in the LLM era.

Active1541 month ago
Python

Fine-tuned version of google/gemma-4-E4B-it across three professional domains — Medical, Legal, and Finance — using QLoRA (4-bit NF4) with Optuna-tuned hyperparameters, trained on Kaggle T4 GPU.

Active1K1 month ago
Python

# or·a·cle /ˈôrəkəl/ — a source of wise counsel; one who provides authoritative knowledge. From Latin ōrāculum, meaning divine announcement. In computer science, an oracle is a black box that always returns the correct answer — you don't ask it how it knows, you ask and it answers.

Active1422 months ago
Python

A compact protein language model distilled from ProtGPT2 using complementary-regularizer distillation---a method that combines uncertainty-aware position weighting with calibration-aware label smoothing to achieve 31% better perplexity than standard knowledge distillation at 3.8x compression.

Active733 months ago
Python

A compact protein language model distilled from ProtGPT2 using complementary-regularizer distillation---a method that combines uncertainty-aware position weighting with calibration-aware label smoothing to achieve 54% better perplexity than standard knowledge distillation at 9.4x compression.

Active53 months ago
Python

A compact protein language model distilled from ProtGPT2 using complementary-regularizer distillation---a method that combines uncertainty-aware position weighting with calibration-aware label smoothing to achieve 87% better perplexity than standard knowledge distillation at 20x compression.

Active143 months ago
Python

From Inquiry to Decision: Building Trustworthy Medical AI

Active204 months ago
Python
Active454 months ago
Python

The MediPhi Model Collection comprises 7 small language models of 3.8B parameters from the base model Phi-3.5-mini-instruct specialized in the medical and clinical domains. The collection is designed in a modular fashion. Five MediPhi experts are fine-tuned on various medical corpora (i.e.

Active2K5 months ago
Python

GitHub homepage: Cell2Sentence GitHub

Idle9607 months ago
Python

中文版说明

Idle779 months ago
Python

Neeto-1.0-8b is an openly released biomedical large language model (LLM) created by BYOL Academy to assist learners and practitioners with medical exam study, literature understanding, and structured clinical reasoning.

Idle7.7K9 months ago
Python

darkknight25/deepseek-16b-medical-GPT is a fine-tuned version of deepseek-ai/deepseek-l6b-moe-chat, optimized for medical question answering, reasoning, and clinical summarization using QLoRA and open-access healthcare datasets.

Idle010 months ago
Python

Dans-PersonalityEngine-V1.3.0-24b Dans-PersonalityEngine-V1.3.0-24b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀…

Idle1851 year ago
Python

Dans-PersonalityEngine-V1.2.0-24b ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⢀⠀⠄⠀⡂⠀⠁⡄⢀⠁⢀⣈⡄⠌⠐⠠⠤⠄⡀⠀⠀⠀⠀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⡄⠆⠀⢠⠀⠛⣸⣄⣶⣾⡷⡾⠘⠃⢀⠀⣴⠀⡄⠰⢆⣠⠘⠰⠀⡀⠀⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠃⠀⡋⢀⣤⡿⠟⠋⠁⠀⡠⠤⢇⠋⠀⠈⠃⢀⠀⠈⡡⠤⠀⠀⠁⢄⠀⠀⠀⠀ ⠀⠀⠀⠀⠀⠁⡂⠀⠀⣀⣔⣧⠟⠋⠀⢀⡄⠀⠪⣀⡂⢁⠛⢆⠀⠀⠀⢎⢀⠄⢡⠢⠛⠠⡀⠀⠄⠀⠀ ⠀⠀⡀⠡⢑⠌⠈⣧⣮⢾⢏⠁⠀⠀⡀⠠⠦⠈⠀⠞⠑⠁⠀⠀⢧⡄⠈⡜⠷⠒⢸⡇⠐⠇⠿⠈⣖⠂⠀ ⠀⢌⠀⠤⠀⢠⣞⣾⡗⠁⠀⠈⠁⢨⡼⠀⠀⠀⢀⠀⣀⡤⣄⠄⠈⢻⡇⠀⠐⣠⠜⠑⠁⠀⣀⡔⡿⠨⡄…

Idle561 year ago
Python

GP-MoLFormer is a class of models pretrained on SMILES string representations of 0.65-1.1B molecules from ZINC and PubChem. This repository is for the model pretrained on all the unique molecules from both datasets.

Idle1.5K1 year ago
Python

# MMedS-Llama3 💻Github Repo 🖨️arXiv Paper

Idle8941 year ago
Python

# JSL-MedLlama-3-8B-v2.0

Stale6032 years ago
Python

Abstract:

Stale103.9K2 years ago
Python

Abstract:

Stale8752 years ago
Python

SMILES2IUPAC-canonical-base was designed to accurately translate SMILES chemical names to IUPAC standards.

Stale5.1K2 years ago
Python

# ChemGPT 1.2B ChemGPT is based on the GPT-Neo model and was introduced in the paper Neural Scaling of Deep Chemical Models.

Stale3.2K3 years ago
Python

# ChemGPT 19M ChemGPT is based on the GPT-Neo model and was introduced in the paper Neural Scaling of Deep Chemical Models.

Stale2K3 years ago
Python

# ChemGPT 4.7M ChemGPT is based on the GPT-Neo model and was introduced in the paper Neural Scaling of Deep Chemical Models.

Stale3.3K3 years ago
Python