Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

13 of 6,565 resources

Contrastively fine-tuned ESM-C 300M producing fixed-length protein embeddings where biological similarity maps to embedding proximity. Intended for retrieval, clustering, and nearest-neighbour transfer.

Active322 weeks ago
Python

ProtSent-V2 35M plus one more contrastive pass on a fresh draw of the corpus, with a DMS/ProteinGym CoSENT target and a Global Orthogonal Regularization term added.

Active192 weeks ago
Python

Contrastively fine-tuned ESM-2 150M producing fixed-length protein embeddings where biological similarity maps to embedding proximity. Intended for retrieval, clustering, and nearest-neighbour transfer.

Active223 weeks ago
Python

Fine-tuned BGE-M3 on Chinese medical question-answer retrieval using hard negative mining and triple-path InfoNCE loss (dense + sparse + ColBERT).

Active05 months ago

ChemFIE-BED is a sentence-transformers based on gbyuvd/chemselfies-base-bertmlm fine-tuned on around (for now) 2 million pairs of valid molecules' SELFIES (Krenn et al. 2020) taken from COCONUTDB (Sorokina et al. 2021) and ChemBL34 (Zdrazil et al. 2023).

Idle969 months ago
Python

A specialized medical embedding model fine-tuned from Clinical ModernBERT using InfoNCE contrastive learning on PubMed title-abstract pairs.

Idle3.3K1 year ago
Python

INDUS-Retriever-small (previously nasa-smd-ibm-st.38m) is a Bi-encoder sentence transformer model, that is fine-tuned from distilled version of nasa-smd-ibm-v0.1 encoder model. it is a smaller version of nasa-smd-ibm-st with better performance, using fewer parameters (shown below).

Idle111 year ago
Python

# FremyCompany/BioLORD-2023 This model was trained using BioLORD, a new pre-training strategy for producing meaningful representations for clinical sentences and biomedical concepts.

Idle445.3K1 year ago
Python

# FremyCompany/BioLORD-2023-M This model was trained using BioLORD, a new pre-training strategy for producing meaningful representations for clinical sentences and biomedical concepts.

Idle37.9K1 year ago
Python

Indus-Retriever (nasa-smd-ibm-st-v2) is a Bi-encoder sentence transformer model, that is fine-tuned from nasa-smd-ibm-v0.1 encoder model. it is an updated version of nasa-smd-ibm-st with better performance (shown below). It's trained with 271 million examples along with a domain-specific dataset of…

Idle27.9K1 year ago
Python

This model is deprecated. please use the updated sentence transformer model here: https://huggingface.co/nasa-impact/nasa-smd-ibm-st-v2. Alternatively, you can also use distilled version of the model here: https://huggingface.co/nasa-impact/nasa-ibm-st.38m

Stale142 years ago
Python