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A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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Fast Hybrid Assembly of Long Reads. HASLR is a tool for rapid genome assembly of long sequencing reads. HASLR is a hybrid tool which means it requires long reads generated by Third Generation Sequencing technologies (such as PacBio or Oxford Nanopore) together with Next Generation Sequencing reads (such as Illumina) from the same sample. HASLR is capable of assembling large genomes on a single computing node. Our experiments show that it can assemble a CHM1 human dataset in less than 10 hours using 64 CPU threads.
Fast and lightweight assembly-guided scaffolding using minimizer graphs. Scaffolding draft assemblies using reference assemblies and minimizer graphs. ntJoin takes a target assembly and one or more 'reference' assembly as input, and uses information from the reference(s) to scaffold the target assembly. The 'reference' assemblies can be true reference assembly builds, or a different draft genome assemblies.