Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

4 of 7,050 resources

PseudoScope is an automated, locally-executable computational pipeline designed specifically for comprehensive Pseudomonas aeruginosa genomic surveillance. It integrates seven essential analysis modules into a single, cohesive workflow: FASTA QC (assembly quality metrics), MLST (Oxford scheme), PAST serotyping (O-antigen typing), AMRFinderPlus (antimicrobial resistance gene detection), ABRicate (multi-database screening for resistance, virulence, plasmids, biocides), Ultimate Reporter (gene-centric integration with interactive HTML), and Visualisation Dashboard (publication-ready interactive plots including PCA, networks, boxplots). PseudoScope runs entirely locally (or on HPC clusters), protects data privacy, and produces beautiful interactive reports in minutes.

Active102 weeks ago
Python
MIT

Kleboscope is an automated, locally‑executable computational pipeline designed specifically for comprehensive Klebsiella pneumoniae genomic surveillance. It addresses the growing threat of multidrug‑resistant and hypervirulent K. pneumoniae by integrating eight essential analysis modules into a single, cohesive workflow. Kleboscope offers two complementary report views: Gene‑centric – each gene is shown with all genomes that contain it, together with its frequency, enabling rapid cross‑genome pattern discovery; and Sample‑centric – each isolate gets its own interactive box with typing badges (MLST, K‑locus, O‑locus, hypervirulence), per‑database tables (AMR, Virulence, BACMET, Plasmids), and full mutation details – perfect for clinical reports and patient‑level investigations.

Active62 weeks ago
Python
MIT

Local Python sequence utilities for nucleotide composition, DNA and RNA reverse complements, NCBI genetic-code translation, six-frame candidate ORF enumeration, and IUPAC motif searches. Computase accepts raw nucleotide strings or one FASTA record and returns structured, bounded results with explicit scientific conventions.

Active01 month ago
Python
MIT

EcoliTyper is a revolutionary bioinformatics pipeline that eliminates workflow fragmentation in E. coli genomic surveillance. By integrating nine core analyses into a single automated workflow, EcoliTyper transforms disconnected genomic data into coherent biological narratives with actionable public health intelligence. It is a species-optimized computational pipeline for comprehensive genotyping and surveillance of Escherichia coli, perfect for clinical microbiology, outbreak investigations, and genomic research.

Active291 month ago
Python
MIT