Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

4 of 6,573 resources

Open-source AI workbench for scientific research that automates the full research loop β€” literature review, hypothesis generation, code writing, experiment execution, database querying, and report writing β€” with 290+ skills, specialized research agents, and a browser-based workspace (1453+ stars, Apache 2.0, 2026)

Active3.3K1 day ago
TypeScript
Apache-2.0

Local-first, open-source AI workbench for scientists β€” an open alternative to Claude Science (by ai4s-research, maintainers of this list; TypeScript, MIT, 2026)

Active1.4K4 days ago
TypeScript
NOASSERTION

Open-source, local-first, model-agnostic AI research workbench for reproducible scientific discovery; runs Python/R notebooks, searches the web, calls scientific data connectors, and produces inspectable reports, tables, and figures in a self-hosted desktop workspace (1.5K+ stars, Apache 2.0, 2026)

Active1.5K2 weeks ago
TypeScript
Apache-2.0

Free, open-source desktop AI research assistant that runs locally and turns natural-language requests into real data analysis, literature search, figure generation, and manuscript review; ships with 149 scientific skills, 326 workflow templates, and 229 databases across genomics, proteomics, drug discovery, and materials science, plus a living lab notebook, 60+ scientific file previews, and LaTeX editing (K-Dense-AI, 908+ stars, MIT License, 2026)

Active9081 month ago
TypeScript
MIT