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A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.
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Hi-Compass is a depth-aware deep learning framework designed to predict cell-type-specific 3D genome organization and chromatin interactions from chromatin accessibility data (ATAC-seq). It robustly handles data scales from sparse single-cell to high-coverage bulk profiles.
A Bayesian R/Bioconductor package designed for analyzing Chromosome Conformation Capture (Hi-C) data. It identifies significant interactions and models various sources of genomic and technical biases.
HaploC-tools is a computational resource designed to infer and compare whole-chromosome phasing, copy number variants, and chromatin states directly from high-throughput Chromosome Conformation Capture (Hi-C) datasets.
Open-source, containerized workflow and browser (4DGBWorkflow / 4D Genome Browser) that converts Hi-C contact maps (.hic) into 3D chromosome reconstructions and integrates them with epigenomic and transcriptomic track data for comparative, time-resolved visualization of dynamic chromatin architecture.