Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

4 of 6,569 resources

Phylogeny-aware genomic language model trained on whole-genome alignments across multiple evolutionary timescales, predicting functional constraints and variant effects for human, mouse, chicken, fly, worm, and Arabidopsis genomes (344+ stars, MIT License)

Active3491 month ago
Jupyter Notebook
MIT

Single-cell analysis with transformers

Active1.6K3 months ago
Jupyter Notebook
MIT

Generative AI framework for inverse design of 3D RNA structure and function using geometric deep learning, learning design rules from 3D structures to capture complex tertiary interactions (pseudoknots, non-canonical base pairs) with expert-level accuracy for designing functional RNAs including aptamers and ribozymes (bioRxiv 2025)

Idle3138 months ago
Jupyter Notebook
MIT

RNA foundation model trained on millions of RNA sequences for generalist RNA sequence understanding, enabling downstream structure prediction, function annotation, and representation learning for non-coding RNAs (ml4bio, 372+ stars)

Idle3861 year ago
Jupyter Notebook
MIT