Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

11 of 6,358 resources

Scientific taste learning framework showing AI can judge and propose research ideas with long-term impact; trains Scientific Judge as a generative reward model and Scientific Thinker as an ideation policy using Reinforcement Learning from Community Feedback (RLCF) on large-scale citation signals, with SciJudgeBench and released HuggingFace model weights (425+ stars, Apache 2.0, 2026)

Active4254 days ago
Apache-2.0

Scikit-learn compatible tabular foundation model for zero-shot classification and regression on mixed-type tabular datasets via in-context learning; applicable to diverse scientific datasets (1.8K+ stars, Apache 2.0)

Active1.9K1 week ago
Python
Apache-2.0

Pretrained time series foundation model for long-horizon forecasting across diverse scientific domains including climate variables, biomedical signals, and physical observations; decoder-only Transformer architecture with strong zero-shot generalization (19.8K+ stars, Apache 2.0, 2024-2025)

Active26.4K3 weeks ago
Python
Apache-2.0

Pretrained time series foundation model for zero-shot forecasting across diverse scientific and real-world domains; tokenizes continuous time series into discrete bins to train transformer language models on large-scale corpora, achieving strong zero-shot generalization and competitive performance with task-specific supervised models on climate, energy, and health benchmarks (5.3K+ stars, Apache 2.0, 2024-2026)

Active5.6K3 weeks ago
Python
Apache-2.0

First multi-domain generative foundation model for the natural sciences built on a unified scientific grammar, encoding proteins, antibodies, small molecules, chemical reactions, materials, and their spatial interactions into a shared token vocabulary; enables unified generation, prediction, and design across domains under a purely autoregressive paradigm (134+ stars, Apache 2.0, 2026)

Active1341 month ago
Python
Apache-2.0

Foundation model for tabular data that predicts on unseen real-world tables in a single forward pass, achieving accurate small-data classification and regression without task-specific training; widely applicable to scientific datasets with limited samples (7.4K+ stars, 2022-2026)

Active7.4K1 month ago
Python
NOASSERTION

Open-source scientific multimodal foundation model built on a 235B MoE LLM and 6B vision encoder, continually pretrained on 5T tokens including 2.5T scientific-domain tokens, with strong results across chemistry, materials, life science, and earth science benchmarks (2025)

Active8132 months ago
Apache-2.0

Scientific foundation model and AI research copilot for idea generation, cross-disciplinary connection discovery, and hypothesis formation; trained with a decoupled reward-comment RL architecture and achieves GPT-4o-competitive novelty/rationale on STEM and social-science idea-generation benchmarks (270+ stars, MIT License, 2026)

Active2714 months ago
Python
MIT

Open language model for mathematics (7B/34B) trained on Proof-Pile-2, outperforming Minerva at equal scale on MATH benchmark, with tool use and formal theorem proving in Lean without finetuning (EleutherAI, ICLR 2024)

Stale1.1K2 years ago
Python
MIT

Large language model for science

Stale2.7K3 years ago
Jupyter Notebook
Apache-2.0