Find open-source science resources

A directory of tools, AI models, datasets, and research resources for biotech, bioinformatics, and other scientific fields. Aggregated from curated GitHub awesome-lists, HuggingFace, bio.tools, Bioconductor, and more.

8 of 6,750 resources

Noodle is a public, read-only web application for semantic discovery and exploration of biomedical literature sourced from PubMed, Europe PMC, and OpenAlex. It accepts natural-language research questions and presents ranked publications together with gene, genetic variant, and phenotype views. Publication pages provide provenance, identifiers, source links, indexed concepts, and navigable semantic-neighbourhood graphs. The companion Noodle Biomedical Literature Discovery MCP exposes the same public discovery domain through a read-only, source-linked Model Context Protocol interface with bounded citation and semantic graph traversal. Semantic proximity, citation distance, co-mention, and search rank are discovery signals and do not establish scientific evidence, causality, diagnosis, or treatment.

Active01 week ago
Python
Apache-2.0

Inflexa is an open-source, agentic orchestration platform for computational biology and translational medicine. It is designed to assist researchers in analyzing multi-omics, cheminformatics, and imaging data by reading published literature, designing multi-step analysis plans, and executing experiments with full reproducibility.

Active301 week ago
TypeScript
Apache-2.0

Tool for converting raw DNA data files between 23andMe, AncestryDNA, MyHeritage, and FamilyTreeDNA formats.

Active23 months ago
PHP
MIT

k-mer counting, filtering, and graph traversal.

Stale7912 years ago
Python
NOASSERTION

Standalone C library for assembling Illumina short reads in small regions

Stale723 years ago
C
MIT

A cookiecutter template for bioinformatics projects, with a focus on building bioinformatics workflows that can run on the MPI-IE cluster according to FAIR principles.

Stale133 years ago
Python
MIT

This package provides tools for automated sequential gating analogous to the manual gating strategy based on the density of the data.

Reactr is an modularized, Snakemake workflow for automated, species-agnostic characterization of gene families from sequence to experimental design. Given a query protein sequence and NCBI taxonomy IDs (or RefSeq assembly accessions), reactr retrieves genomic data and runs comprehensive analysis across 4 integrated tiers: (1) evolutionary analysis, including homolog detection, domain-based clustering, multiple sequence alignment, and phylogenetic inference; (2) synteny and selection analysis, detecting collinear blocks and calculating Ka/Ks ratios; (3) structural and regulatory characterization, including motif discovery, chromosomal mapping, biochemical property prediction, subcellular localization prediction, and promoter analysis; and (4) experimental design tools, generating PCR primers and scored CRISPR gRNAs for lab validation. Reactr bridges computational prediction and experimental validation, thus enabling rapid transition from genomic discovery to functional studies.